M1249_ASFWA
ID M1249_ASFWA Reviewed; 1249 AA.
AC P0CAB6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 18.
DE RecName: Full=Minor capsid protein M1249L {ECO:0000250|UniProtKB:Q65152};
DE Short=pM1249L;
GN OrderedLocusNames=War-070;
OS African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=561444;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with the penton and the other minor capsid proteins
CC (p17, p49), forms a complicated network immediately below the outer
CC capsid shell, stabilizing the whole capsid.
CC {ECO:0000250|UniProtKB:Q65152}.
CC -!- SUBUNIT: Interacts with the minor capsid protein p17 and with the hexon
CC capsid protein p72 capsomers; these interactions form a rigid zipper
CC structure that stabilizes the capsomers.
CC {ECO:0000250|UniProtKB:Q65152}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q65152}.
CC -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the asfivirus M1249L family. {ECO:0000305}.
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DR EMBL; AY261366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000000858; Genome.
PE 3: Inferred from homology;
KW Late protein; Virion.
FT CHAIN 1..1249
FT /note="Minor capsid protein M1249L"
FT /id="PRO_0000373613"
SQ SEQUENCE 1249 AA; 144479 MW; 68229DB2B3A1D7DA CRC64;
MEEVITIAQI VHRGTDILSL NNEEIEALVD EIYSTLKGSN DIKNIRLIDF LFTLKDFVNH
VRAEQSKLPD LSMPMEAYIR QLLVDSDVVP IVSEKKKELR VRPSTRKEIF LINGTHLAVP
AEAPIEIYGL KLRLKTFSPQ CFMRMAEIGS FSPETLGYVA SGANLTNFIR VFMKCVDQET
WKKNGEGVVV TTKENIIQFT HQYIELYKFL RSGGHSWLIN RLAEEMVHRK LDREDQGSHI
SNIVETEEIE PEENIKRVIF FLKELSTMYS VSPVFTSGYM PLLYDLYRAG YLEVLWNPVE
QKFLQHAEQR EKEQMILQQV DMKLMEVTTQ ARQYFKIMEE KIGRVQSDAI REILTMEGKV
DDPNSILQEV IKACGKQEAE LITTEYLNIK KQWELQEKNA CAHLKLVKQL RSGLQYAESL
KVLESIRVLY KEKNNTTNWN LCKACGFKLL CPHVDMLIQL QAAEASYDTM RTKLMKFSGI
NKEKENNQGL IYSYFCKICG EELAHFIQED RTADVGVIGD LNSKLRIFIW QETMKACTFI
HFGKLVDVKQ FANIAVNVCL PLVYSIENIK KEEDYDPLTQ LYAVIYIYAY ILNLIYSSQK
NKEFLTITIH GMKADSSLNA YVTFLLEKMM QQYSGIINQL SEITDQWIAN NFREAFKKII
HQNGLQGLSV QDDTKVLLTE ILLDPMYDYA ATVARIDGSI PMHKPRTPKE AEYEFKTVIG
RTPAELLSQK EFYDKIYTSK YRPDFTQLAR LKDIYFQEES LRVWWGGRDE EKTSTLIYLR
AYELFLKYLQ NAPNFNSELA EFKTYENAYG EQKALLAQQG FYNIFDPNTG RADQRTRLFE
YKRLPISTLY DERGLPHKWT IYVYKAVDSS QKPTEIEVTR KDVIKKIDNH YALADLRCSV
CHVLQHEVGQ LNIKKVQTAL KASLEFNTFY AFYESRCPKG GLHDFQDKKC VKCGLFTYII
YDHLSQPELV HDYYNNYKDQ YDKEKMSIRS IQIKKDMTMP STETQPKPPQ EPWTFDYGKI
IKTAKILDIS PAVIEAIGAM EGRSYADIRE GQGAPPPPTS MDDPRLMAVD SAVRIFLYNY
NCLRHVSTFN KPPMHVERLV KHLSYEEKED LEKVLPNVVN EYHTTFKHLR VTDPASALLY
SIEFLCISFL TLYDIKEPSW VVNIVREFAL TELNTIIQSE KLLSKPGAFN FMIFGEDFVC
SGEDSSMDDI SAYSSPGLFG EDIIDRLDDP FSIEDVDISL DVLDNLAPQ