ID   M130_STRPU              Reviewed;         779 AA.
AC   P08472;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 2.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Mesenchyme-specific cell surface glycoprotein;
DE   AltName: Full=MSP130;
DE   Flags: Precursor;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=2295637; DOI=10.1016/s0021-9258(19)40029-x;
RA   Parr B.A., Parks A.L., Raff R.A.;
RT   "Promoter structure and protein sequence of msp130, a lipid-anchored sea
RT   urchin glycoprotein.";
RL   J. Biol. Chem. 265:1408-1413(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 542-779.
RX   PubMed=3569664; DOI=10.1016/0012-1606(87)90135-7;
RA   Leaf D.S., Anstrom J.A., Chin J.E., Harkey M.A., Showman R.M., Raff R.A.;
RT   "Antibodies to a fusion protein identify a cDNA clone encoding msp130, a
RT   primary mesenchyme-specific cell surface protein of the sea urchin
RT   embryo.";
RL   Dev. Biol. 121:29-40(1987).
CC   -!- FUNCTION: Not known. Could be involved in mesenchyme cell migration,
CC       adhesion, fusion, or spicule formation.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Restricted to the primary mesenchyme cell lineage.
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DR   EMBL; M31750; AAA30065.1; -; Genomic_DNA.
DR   EMBL; M31751; AAA30066.1; -; mRNA.
DR   EMBL; M16457; AAA30064.1; -; mRNA.
DR   PIR; A35006; A35006.
DR   AlphaFoldDB; P08472; -.
DR   eggNOG; ENOG502S02S; Eukaryota.
DR   HOGENOM; CLU_336276_0_0_1; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW   Reference proteome; Repeat; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..779
FT                   /note="Mesenchyme-specific cell surface glycoprotein"
FT                   /id="PRO_0000021631"
FT   REGION          249..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..303
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        203
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        234
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        369
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        451
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        609
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   779 AA;  81006 MW;  7D522D8348928316 CRC64;
     MQFGVPLLVL CLALGSTEAT ISLKLVSRLY LPFDKLPVGG GAGGAGGAGG AGGGGGGGGG
     AGGRGGGGGG RGQTGGMYAL NNGVAFKSAY DMDKQLAYVG GGQFVQIVDF SDVVQPKVVK
     QIATEGPVAD IAECGDLVAF TQPGKPHFTD VGSLKIYEKY NPATMMMKEL CSVEVGSQPI
     AVRFAQGCSL IIVANEGVMG ENNYTKKYVN PEGTITTVRL AGSVSNGPSQ QIVNTTFGAG
     GPMMTTPMAG FPRGTTWSPN AGAGGQGGQG QYPGQGGQGG QGGQGGQGQY PGQGGQGGQG
     GQGGQGGQGG YPGQGGQGGP GYYPGQGGQG GQGGQGGWGQ GGGQGGQGGG NNPQYPMIPT
     TPLPGTICNG TSTMSYVVSQ INFHKFNAPA EVQRLKALHV RQPYTGQLGD PGPHTFSRGL
     EPRHITLDQQ EQIAYISLQE NNAIAVVDLN NNTVIDILPM GVKNWKGLKI DASSADRGIL
     FQTYDQLNSF PMPDAIETYY DAMGDLYVVT ANEGAKPMMA QCSLEVCPGG PGEFEEVEIG
     EEFIVEELLP QPVIDSPLGQ AMAEETQLGS SLFSMVDGIN PAEPEFFNEV FMFGGRGISA
     YKVDPITMNM TLAWDSGDVI EKEIAKFFPK IFNGAAFSRP PQRVKPFMTK DSRSSGRGPE
     CESLAVGDVQ GRKLIFVGID GVSALAIFSV APGNSTPVYE SLFKDGHIDA SYNALYKNRK
     TGRVSGTVSM YEVIDVPYWM LLKTLGTNIE GSSAISMTSS AFSIFFAFLS GMFAIFMKM