ID   M17L2_BOVIN             Reviewed;         218 AA.
AC   A5D787;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Mpv17-like protein 2;
GN   Name=MPV17L2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the assembly and stability of the mitochondrial
CC       ribosome (By similarity). Is a positive regulator of mitochondrial
CC       protein synthesis (By similarity). {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SUBUNIT: Interacts with the large mitochondrial ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; BC140467; AAI40468.1; -; mRNA.
DR   RefSeq; NP_001091614.1; NM_001098145.2.
DR   AlphaFoldDB; A5D787; -.
DR   STRING; 9913.ENSBTAP00000036320; -.
DR   PaxDb; A5D787; -.
DR   PRIDE; A5D787; -.
DR   GeneID; 618791; -.
DR   KEGG; bta:618791; -.
DR   CTD; 84769; -.
DR   eggNOG; KOG1944; Eukaryota.
DR   HOGENOM; CLU_049109_4_1_1; -.
DR   InParanoid; A5D787; -.
DR   OrthoDB; 1324608at2759; -.
DR   TreeFam; TF324392; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0061668; P:mitochondrial ribosome assembly; IBA:GO_Central.
DR   GO; GO:0070131; P:positive regulation of mitochondrial translation; ISS:UniProtKB.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PTHR11266; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..218
FT                   /note="Mpv17-like protein 2"
FT                   /id="PRO_0000317620"
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   218 AA;  24535 MW;  41914124140DF072 CRC64;
     MPPGGWRWLR GLWAAGQPLF QGRALLVTNT LGCGVLMAAG DGARQTWEIR ARPGQKFDPR
     RSVSMFAVGC SMGPFLHYWY LWLDRLFPAS GFPGLPNVLK KVLIDQLVAS PMLGVWYFLG
     LGCLEGQTLD KSCQELRDKF WEFYKADWCV WPAAQLVNFL FVPPQFRVTY INGLTLGWDT
     YLSYLKYRIP GPLTPPGCVA LGTIQTEPPD ARQQGKTD