ID   M17L2_XENTR             Reviewed;         222 AA.
AC   Q6DIY8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Mpv17-like protein 2;
GN   Name=mpv17l2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the assembly and stability of the mitochondrial
CC       ribosome (By similarity). Is a positive regulator of mitochondrial
CC       protein synthesis (By similarity). {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SUBUNIT: Interacts with the large mitochondrial ribosomal subunit.
CC       {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q567V2}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; BC075397; AAH75397.1; -; mRNA.
DR   RefSeq; NP_001004930.1; NM_001004930.1.
DR   AlphaFoldDB; Q6DIY8; -.
DR   PaxDb; Q6DIY8; -.
DR   PRIDE; Q6DIY8; -.
DR   DNASU; 448319; -.
DR   Ensembl; ENSXETT00000039669; ENSXETP00000039669; ENSXETG00000018317.
DR   GeneID; 448319; -.
DR   KEGG; xtr:448319; -.
DR   CTD; 84769; -.
DR   Xenbase; XB-GENE-1002324; mpv17l2.
DR   eggNOG; KOG1944; Eukaryota.
DR   HOGENOM; CLU_049109_4_1_1; -.
DR   InParanoid; Q6DIY8; -.
DR   OMA; FMPLAYR; -.
DR   OrthoDB; 1324608at2759; -.
DR   PhylomeDB; Q6DIY8; -.
DR   TreeFam; TF324392; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000018317; Expressed in ovary and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0061668; P:mitochondrial ribosome assembly; IBA:GO_Central.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PTHR11266; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..222
FT                   /note="Mpv17-like protein 2"
FT                   /id="PRO_0000317624"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   222 AA;  25755 MW;  A364F993D4E35574 CRC64;
     MIPLGKLVLA RAAGYWKPFF KGRFLIVTNT VSCGLLLGIG DSIQQSREVR RDPERKRDWL
     RTGRMFAIGC SMGPLMHFWY SWLDRSFPGR GITVVMRKVL IDQLVASPVL GLWYFLGMGS
     MEGQKLEKSW QEFREKFWEF YKADWTVWPA AQMINFYFLS PKYRVIYINV ITVGWDTYLS
     YLKHRKEECV ENTMGTSSFG TLDELDSCST PLPKTLDESG QP