M1I1B_DANRE
ID M1I1B_DANRE Reviewed; 147 AA.
AC Q1LUV9; Q6P955;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720};
GN Name=mid1ip1b {ECO:0000312|ZFIN:ZDB-GENE-040426-1720};
GN ORFNames=si:dkey-277i15.1, zgc:73223;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2] {ECO:0000312|EMBL:CAK10925.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Retina {ECO:0000312|EMBL:AAH60921.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in stabilization of microtubules. May play a role in
CC the regulation of lipogenesis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9CQ20}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q9CQ20}. Cytoplasm, cytoskeleton {ECO:0000250}.
CC Note=Associated with microtubules. {ECO:0000250|UniProtKB:Q9CQ20}.
CC -!- SIMILARITY: Belongs to the SPOT14 family. {ECO:0000255}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-2 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH60921.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BX927146; CAK10925.1; -; Genomic_DNA.
DR EMBL; BC060921; AAH60921.1; ALT_INIT; mRNA.
DR RefSeq; NP_957126.1; NM_200832.1.
DR AlphaFoldDB; Q1LUV9; -.
DR SMR; Q1LUV9; -.
DR STRING; 7955.ENSDARP00000021980; -.
DR PaxDb; Q1LUV9; -.
DR Ensembl; ENSDART00000007649; ENSDARP00000021980; ENSDARG00000019302.
DR GeneID; 393805; -.
DR KEGG; dre:393805; -.
DR CTD; 393805; -.
DR ZFIN; ZDB-GENE-040426-1720; mid1ip1b.
DR eggNOG; ENOG502S0KR; Eukaryota.
DR GeneTree; ENSGT00500000044890; -.
DR HOGENOM; CLU_066079_1_0_1; -.
DR InParanoid; Q1LUV9; -.
DR OMA; RRDMYSH; -.
DR OrthoDB; 1326063at2759; -.
DR PhylomeDB; Q1LUV9; -.
DR TreeFam; TF326826; -.
DR Reactome; R-DRE-200425; Carnitine metabolism.
DR PRO; PR:Q1LUV9; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 22.
DR Bgee; ENSDARG00000019302; Expressed in muscle tissue and 52 other tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0140496; F:gamma-tubulin complex binding; IDA:ZFIN.
DR GO; GO:0072175; P:epithelial tube formation; IMP:ZFIN.
DR GO; GO:0061842; P:microtubule organizing center localization; IMP:ZFIN.
DR GO; GO:0046890; P:regulation of lipid biosynthetic process; IBA:GO_Central.
DR InterPro; IPR009786; Spot_14.
DR PANTHER; PTHR14315; PTHR14315; 1.
DR Pfam; PF07084; Spot_14; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Microtubule; Nucleus; Reference proteome.
FT CHAIN 1..147
FT /note="Mid1-interacting protein 1-B"
FT /id="PRO_0000389525"
SQ SEQUENCE 147 AA; 16811 MW; 77DE3EC01C60D17A CRC64;
MMQICDSYNQ KNSLFNAMNR FIGAVNNMDQ TVMVPSLLRD VPLDQEEEKE VTSFQDGDMY
GSYVLLKSIR NDIEWGVLQA EERRKEKHGV TTTSLEVSRI EPNDKDLEKL FHYHLSGLHT
VLAKLTRKAN TLTNRYKQEI GIGGCGN
