ID   M2_VACCC                Reviewed;         220 AA.
AC   P21092;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 56.
DE   RecName: Full=Protein M2;
DE   Flags: Precursor;
GN   ORFNames=M2L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- SIMILARITY: Belongs to the poxviridae M2 protein family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48004.1; -; Genomic_DNA.
DR   PIR; H42504; H42504.
DR   Proteomes; UP000008269; Genome.
DR   InterPro; IPR006971; Poxvirus_M2.
DR   Pfam; PF04887; Pox_M2; 1.
DR   PIRSF; PIRSF015982; VAC_M2L; 1.
PE   3: Inferred from homology;
KW   Early protein; Reference proteome; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..220
FT                   /note="Protein M2"
FT                   /id="PRO_0000099630"
SQ   SEQUENCE   220 AA;  25108 MW;  EB0C5EE7575D88DF CRC64;
     MVYKLVLLFC IASLGYSVEY KNTICPPRQD YRYWYFAAEL TIGVNYDINS TIIGECHMSE
     SYIDRNANIV LTGYGLEINM TIMDTDQRFV AAAEGVGKDN KLSVLLFTTQ RLDKVHHNIS
     VTITCMEMNC GTTKYDSDLP ESIHKSSSCD ITINGSCVTC VNLETDPTKI NPHYLHPKDK
     YLYHNSEYGM RGSYGVTFID ELNQCLLDIK ELSYDICYRE