ID   M3C_CONFI               Reviewed;          14 AA.
AC   P0DP11;
DT   12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 1.
DT   22-APR-2020, entry version 10.
DE   RecName: Full=Conotoxin Fi3c {ECO:0000303|PubMed:25420928};
OS   Conus figulinus (Fig cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Dendroconus.
OX   NCBI_TaxID=101301;
RN   [1]
RP   PROTEIN SEQUENCE, IDENTIFICATION BY MASS SPECTROMETRY, MASS SPECTROMETRY,
RP   AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=25420928; DOI=10.1002/psc.2715;
RA   Rajesh R.P.;
RT   "Novel M-Superfamily and T-Superfamily conotoxins and contryphans from the
RT   vermivorous snail Conus figulinus.";
RL   J. Pept. Sci. 21:29-39(2015).
CC   -!- FUNCTION: May act as a neurotoxin. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:25420928}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:25420928}.
CC   -!- DOMAIN: The cysteine framework is III (CC-C-C-CC). Classified in the M-
CC       2 branch, since 4 residues stand between the fourth and the fifth
CC       cysteine residues. {ECO:0000305}.
CC   -!- PTM: Contains 3 disulfide bonds. {ECO:0000269|PubMed:25420928}.
CC   -!- MASS SPECTROMETRY: Mass=1409.8; Method=Unknown;
CC       Evidence={ECO:0000269|PubMed:25420928};
CC   -!- SIMILARITY: Belongs to the conotoxin M superfamily. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Neurotoxin; Secreted; Toxin.
FT   PEPTIDE         1..14
FT                   /note="Conotoxin Fi3c"
FT                   /evidence="ECO:0000269|PubMed:25420928"
FT                   /id="PRO_0000439622"
FT   DISULFID        1..13
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
FT   DISULFID        2..9
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
FT   DISULFID        6..12
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
FT   UNSURE          10
FT                   /note="I or L"
FT                   /evidence="ECO:0000305|PubMed:25420928"
SQ   SEQUENCE   14 AA;  1417 MW;  D0BD08E5ED832DCD CRC64;
     CCSTNCAVCI PCCP