ID   M4A10_PONAB             Reviewed;         264 AA.
AC   Q5REZ6;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 10;
GN   Name=MS4A10;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in signal transduction as a component of a
CC       multimeric receptor complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MS4A family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR857366; CAH89661.1; -; mRNA.
DR   AlphaFoldDB; Q5REZ6; -.
DR   STRING; 9601.ENSPPYP00000003697; -.
DR   PRIDE; Q5REZ6; -.
DR   eggNOG; ENOG502SH2M; Eukaryota.
DR   HOGENOM; CLU_1041911_0_0_1; -.
DR   InParanoid; Q5REZ6; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007237; CD20-like.
DR   InterPro; IPR030417; MS4A.
DR   PANTHER; PTHR23320; PTHR23320; 1.
DR   Pfam; PF04103; CD20; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..264
FT                   /note="Membrane-spanning 4-domains subfamily A member 10"
FT                   /id="PRO_0000238678"
FT   TOPO_DOM        1..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        79..89
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        111..119
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..169
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        191..264
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          17..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   264 AA;  29387 MW;  934364F23D7CCDEF CRC64;
     MKAEATVIPS RCARGQTTAA PGVQPWQTSV PQNTTQPKLL APRQHEKSQK RSSLLKELGA
     FHITIALLHL VFGGYLASTV KSLHLVVLKS WYPFWGAASF LISGILAITM KTFSKTYLKM
     LCLMTNLVSL FCVLSGLFVI SKDLFLESPF ESPIWRMYPN STVHIQRLEL ALLCFTVLEL
     FLPVPTAVTA WRDRPSAKND DACLLPNTPS HLKGLPVEPP PSYQSVIQGD AQHKQHQRLR
     EVKQVTPDTW IVTDGAGIWT QTAN