ID   M4GDB_XENLA             Reviewed;         223 AA.
AC   Q801N6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=MIF4G domain-containing protein B;
GN   Name=mif4gd-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions in replication-dependent translation of histone
CC       mRNAs which differ from other eukaryotic mRNAs in that they do not end
CC       with a poly-A tail but a stem-loop. May participate in circularizing
CC       those mRNAs specifically enhancing their translation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with eif4g1, eif4g2 and slbp; probably tethered by
CC       SLBP to the 3'-end of mRNAs ending with the histone stem-loop, it also
CC       interacts with eif4g1 which is bound to their 5'-end. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MIF4GD family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC048773; AAH48773.1; -; mRNA.
DR   RefSeq; NP_001079711.1; NM_001086242.1.
DR   AlphaFoldDB; Q801N6; -.
DR   SMR; Q801N6; -.
DR   ComplexPortal; CPX-1311; SLBP1-SLIP1 complex.
DR   DNASU; 379398; -.
DR   GeneID; 379398; -.
DR   KEGG; xla:379398; -.
DR   CTD; 379398; -.
DR   Xenbase; XB-GENE-6256062; mif4gd.S.
DR   OMA; KVNSQRM; -.
DR   OrthoDB; 1168859at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 379398; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IC:ComplexPortal.
DR   GO; GO:0062073; C:histone mRNA stem-loop binding complex; IC:ComplexPortal.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0002191; P:cap-dependent translational initiation; IC:ComplexPortal.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   Pfam; PF02854; MIF4G; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Translation regulation.
FT   CHAIN           1..223
FT                   /note="MIF4G domain-containing protein B"
FT                   /id="PRO_0000337095"
FT   DOMAIN          9..206
FT                   /note="MIF4G"
SQ   SEQUENCE   223 AA;  25741 MW;  BE6A456280449F8C CRC64;
     MADSEEQEDY KIQGFDADIQ NLLKTALKEP GSVDLEKAAN VIVDQSLRDS TFSREAGRMC
     YTIIQVESKQ TGCTMFRSSL LNRLQVEYRN RKETRARSLQ EWVCYVGFMC NVFDYLRVNN
     MPMLALVNPV YDCLFDLVQP DSLKKEVEVD CLVLQLHRVG EQLEKMNCQR MDELFSQLRD
     GFLLQGGLSS LTQLLLLEMI EYRAAGWSMT DAAQKYYYSE VSD