M556_METJA
ID M556_METJA Reviewed; 174 AA.
AC Q57976;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Methylated protein MJ0556;
GN OrderedLocusNames=MJ0556;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND METHYLATION.
RX PubMed=14976258; DOI=10.1073/pnas.0306575101;
RA Forbes A.J., Patrie S.M., Taylor G.K., Kim Y.-B., Jiang L., Kelleher N.L.;
RT "Targeted analysis and discovery of posttranslational modifications in
RT proteins from methanogenic archaea by top-down MS.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2678-2683(2004).
CC -!- PTM: Methylated at an undetermined residue between Ser-2 and Asp-26.
CC {ECO:0000269|PubMed:14976258}.
CC -!- MASS SPECTROMETRY: Mass=20207; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:14976258};
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB98550.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; L77117; AAB98550.1; ALT_INIT; Genomic_DNA.
DR PIR; D64369; D64369.
DR RefSeq; WP_064496541.1; NC_000909.1.
DR AlphaFoldDB; Q57976; -.
DR SMR; Q57976; -.
DR STRING; 243232.MJ_0556; -.
DR EnsemblBacteria; AAB98550; AAB98550; MJ_0556.
DR GeneID; 1451421; -.
DR KEGG; mja:MJ_0556; -.
DR eggNOG; arCOG02569; Archaea.
DR HOGENOM; CLU_1431673_0_0_2; -.
DR InParanoid; Q57976; -.
DR OMA; IIFMEDI; -.
DR OrthoDB; 99405at2157; -.
DR PhylomeDB; Q57976; -.
DR Proteomes; UP000000805; Chromosome.
DR Gene3D; 3.10.580.10; -; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR Pfam; PF00571; CBS; 2.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; SSF54631; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 1: Evidence at protein level;
KW CBS domain; Methylation; Reference proteome; Repeat.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000305"
FT CHAIN 2..174
FT /note="Methylated protein MJ0556"
FT /id="PRO_0000106929"
FT DOMAIN 28..87
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 91..156
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ SEQUENCE 174 AA; 20352 MW; 984DEF1163F322ED CRC64;
MSKFVKLHLV RTLNKYKELQ KIRVKDVMIS GDVIITTPEK TIKEIFDEMI KHNISGMPVV
DDRGVMIGFI TLREIRKYMT SHPYLNVGEV MLKNPPYTTA DEDIITAFEK MIESNKKLDQ
LPVINTKYPE KILGKLEGII FMEDIIKLLY ENIIKELKTL VSFYNHNTEI KIKY