ID   M5_CONTE                Reviewed;          19 AA.
AC   P86263;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 21.
DE   RecName: Full=Conotoxin 5 {ECO:0000250|UniProtKB:P0C424};
OS   Conus textile (Cloth-of-gold cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Cylinder.
OX   NCBI_TaxID=6494;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS
RP   SPECTROMETRY, AND DISULFIDE BONDS.
RC   TISSUE=Venom;
RX   PubMed=19380747; DOI=10.1073/pnas.0900745106;
RA   Ueberheide B.M., Fenyo D., Alewood P.F., Chait B.T.;
RT   "Rapid sensitive analysis of cysteine rich peptide venom components.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19380747}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000269|PubMed:19380747}.
CC   -!- DOMAIN: The cysteine framework is III (CC-C-C-CC). Classified in the M-
CC       2 branch, since 2 residues stand between the fourth and the fifth
CC       cysteine residues.
CC   -!- PTM: Contains 3 disulfide bonds.
CC   -!- MASS SPECTROMETRY: Mass=2016.74; Mass_error=0.02; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:19380747};
CC   -!- SIMILARITY: Belongs to the conotoxin M superfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P86263; -.
DR   ConoServer; 3748; Tx3g.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   PEPTIDE         1..19
FT                   /note="Conotoxin 5"
FT                   /id="PRO_0000371278"
FT   DISULFID        2..18
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
FT   DISULFID        3..14
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
FT   DISULFID        8..17
FT                   /evidence="ECO:0000250|UniProtKB:P0CI24"
SQ   SEQUENCE   19 AA;  2024 MW;  662339D28AFC2238 CRC64;
     GCCHPSTCHV RKGCSRCCS