MA657_ARATH
ID MA657_ARATH Reviewed; 603 AA.
AC Q8L836; Q67Z18; Q9LQW1;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=65-kDa microtubule-associated protein 7;
DE Short=AtMAP65-7;
GN Name=MAP65-7; OrderedLocusNames=At1g14690; ORFNames=F10B6.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 159-603.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12516862; DOI=10.1023/a:1021236307508;
RA Hussey P.J., Hawkins T.J., Igarashi H., Kaloriti D., Smertenko A.;
RT "The plant cytoskeleton: recent advances in the study of the plant
RT microtubule-associated proteins MAP-65, MAP-190 and the Xenopus MAP215-like
RT protein, MOR1.";
RL Plant Mol. Biol. 50:915-924(2002).
CC -!- SUBUNIT: Forms dimer. Binds to microtubules (MT) (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MAP65/ASE1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79248.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006917; AAF79248.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29208.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29209.1; -; Genomic_DNA.
DR EMBL; AY120768; AAM53326.1; -; mRNA.
DR EMBL; BT008373; AAP37732.1; -; mRNA.
DR EMBL; AK176215; BAD43978.1; -; mRNA.
DR EMBL; AK176300; BAD44063.1; -; mRNA.
DR RefSeq; NP_001077537.1; NM_001084068.3.
DR RefSeq; NP_172922.2; NM_101338.4.
DR AlphaFoldDB; Q8L836; -.
DR SMR; Q8L836; -.
DR STRING; 3702.AT1G14690.1; -.
DR iPTMnet; Q8L836; -.
DR PaxDb; Q8L836; -.
DR PRIDE; Q8L836; -.
DR ProteomicsDB; 238871; -.
DR EnsemblPlants; AT1G14690.1; AT1G14690.1; AT1G14690.
DR EnsemblPlants; AT1G14690.2; AT1G14690.2; AT1G14690.
DR GeneID; 838034; -.
DR Gramene; AT1G14690.1; AT1G14690.1; AT1G14690.
DR Gramene; AT1G14690.2; AT1G14690.2; AT1G14690.
DR KEGG; ath:AT1G14690; -.
DR Araport; AT1G14690; -.
DR TAIR; locus:2006737; AT1G14690.
DR eggNOG; KOG4302; Eukaryota.
DR HOGENOM; CLU_011760_2_0_1; -.
DR InParanoid; Q8L836; -.
DR OMA; EYNQDET; -.
DR OrthoDB; 272248at2759; -.
DR PhylomeDB; Q8L836; -.
DR PRO; PR:Q8L836; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8L836; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IBA:GO_Central.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR InterPro; IPR007145; MAP65_Ase1_PRC1.
DR PANTHER; PTHR19321; PTHR19321; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Nucleus; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..603
FT /note="65-kDa microtubule-associated protein 7"
FT /id="PRO_0000395478"
FT REGION 501..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 48..79
FT /evidence="ECO:0000255"
FT COILED 131..186
FT /evidence="ECO:0000255"
FT COILED 468..502
FT /evidence="ECO:0000255"
FT COMPBIAS 511..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 419
FT /note="Microtubule binding"
FT /evidence="ECO:0000250"
FT SITE 430
FT /note="Microtubule binding"
FT /evidence="ECO:0000250"
FT MOD_RES 513
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9FLP0"
FT MOD_RES 599
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9FLP0"
SQ SEQUENCE 603 AA; 69061 MW; 7C2B37A23CBB889D CRC64;
MLEIESPTSL CFRTNTTCNA LLRELQKIWV DIGESDAEKD RMLMELEKEC LEIYRRKVDE
AANSKAQLHQ SLVSIEAEIA SLLAALGVFN SHSPMKAKEG SKSLKEKLAA VRPMLEDLRL
QKDERMKQFV DIKAQIEKMS GEISGYSDQL NKTMVGSLAL DEQDLTLRKL NEYQTHLRSL
QKEKSDRLNK VLDYVNEVHT LCGVLGVDFG QTVSEVHPSL HRTDHEQSTN ISDDTLDGLH
HMIHKLKTER SVRFQKLKDV AGSLFELWNL MDTSQEERTK FASVSYVVRS SESDITEPNI
LSSETIEQVS AEVDCFNKLK ASRMKELVMK RRTELENLCR LAHIEADTST SLEKSTALID
SGLVDPSELL TNIELHINKI KEEAHSRKEI IDRIDRWLSA CEEENWLEEY NQDETRYSAG
RGGHVNLKHA ERARITVNKI PSMVDNLIKK TLLWEDETRK SFLYDGVRLV SILEDYKLTR
KQQEEEKRRY RDQKKMQDLL IKRRESIYGS KPSPRRSNSV RKTNGYNGDA SVPPTPRRNS
AGATNNDIMT TPRSYSSHRQ NGYFKEVRRL STAPLNFVAI PKEDSVSTYT SVCGSEPDSP
LYN
