MA6D1_BOVIN
ID MA6D1_BOVIN Reviewed; 192 AA.
AC Q0P591;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=MAP6 domain-containing protein 1;
GN Name=MAP6D1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hippocampus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May have microtubule-stabilizing activity. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with calmodulin. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasm, cytoskeleton
CC {ECO:0000250}. Note=Colocalizes with microtubules. {ECO:0000250}.
CC -!- PTM: Palmitoylated. Palmitoylation enhances association with
CC microtubules (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the STOP family. {ECO:0000305}.
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DR EMBL; BC120336; AAI20337.1; -; mRNA.
DR RefSeq; NP_001069822.1; NM_001076354.1.
DR RefSeq; XP_015327772.1; XM_015472286.1.
DR AlphaFoldDB; Q0P591; -.
DR STRING; 9913.ENSBTAP00000043113; -.
DR PaxDb; Q0P591; -.
DR Ensembl; ENSBTAT00000045750; ENSBTAP00000043113; ENSBTAG00000014459.
DR GeneID; 614904; -.
DR KEGG; bta:614904; -.
DR CTD; 79929; -.
DR VEuPathDB; HostDB:ENSBTAG00000014459; -.
DR VGNC; VGNC:31209; MAP6D1.
DR eggNOG; ENOG502RXB9; Eukaryota.
DR GeneTree; ENSGT00530000063947; -.
DR HOGENOM; CLU_089524_0_0_1; -.
DR InParanoid; Q0P591; -.
DR OMA; PREDYQP; -.
DR OrthoDB; 1408472at2759; -.
DR TreeFam; TF338320; -.
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000014459; Expressed in midbrain and 100 other tissues.
DR GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR GO; GO:0005798; C:Golgi-associated vesicle; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR GO; GO:0018009; P:N-terminal peptidyl-L-cysteine N-palmitoylation; IEA:Ensembl.
DR GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IBA:GO_Central.
DR InterPro; IPR007882; MAP6.
DR PANTHER; PTHR14759; PTHR14759; 1.
PE 2: Evidence at transcript level;
KW Calmodulin-binding; Cytoplasm; Cytoskeleton; Golgi apparatus; Lipoprotein;
KW Palmitate; Phosphoprotein; Reference proteome.
FT CHAIN 1..192
FT /note="MAP6 domain-containing protein 1"
FT /id="PRO_0000271914"
FT REGION 36..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 38
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q14BB9"
FT MOD_RES 160
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q14BB9"
FT LIPID 5
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 10
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 11
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 192 AA; 20611 MW; 5FB4CC12C8E9C438 CRC64;
MAWPCISRLC CLARRWNQLD RSDVAVPLTL HSYSDLESEE PIPGGVPSRR GPSPAGSRDP
GRDVPLTQYQ RDFGVWTAPS GSRDATQGRG PGASSRRTKP SATPGRGVYV LPIGDADAAA
VATTSYRQEF QAWTGVKPSR STKVKPAKVI TTHSSGWDGS PRAGFQAPEV RKKFAPNPSA
IFQASAPRIL NV
