ID   MAAY1_SCHCO             Reviewed;         891 AA.
AC   P37936;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Mating-type protein A-alpha Y1;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UVM 9-1;
RX   PubMed=1353886; DOI=10.1073/pnas.89.15.7169;
RA   Stankis M.M., Specht C.A., Yang H., Giasson L., Ullrich R.C., Novotny C.P.;
RT   "The A alpha mating locus of Schizophyllum commune encodes two dissimilar
RT   multiallelic homeodomain proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:7169-7173(1992).
CC   -!- FUNCTION: Specifies A-alpha-1 mating-type. May regulate the expression
CC       of genes specific to the homokaryotic cell type.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- DEVELOPMENTAL STAGE: Expressed constitutively in homokaryons.
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DR   EMBL; M97179; AAB01367.1; -; Genomic_DNA.
DR   PIR; A46203; A46203.
DR   AlphaFoldDB; P37936; -.
DR   SMR; P37936; -.
DR   PRIDE; P37936; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0019953; P:sexual reproduction; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR007689; AalphaY_mating_typ-dep-bd-dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF04611; AalphaY_MDB; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..891
FT                   /note="Mating-type protein A-alpha Y1"
FT                   /id="PRO_0000049187"
FT   DNA_BIND        146..205
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          241..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          319..339
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          393..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          610..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          800..822
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..640
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..664
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..714
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        800..818
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   891 AA;  97409 MW;  4F747E0D05C8A2D7 CRC64;
     MTDRLASLRA ISASAKSMMS IAAARGAQPT APIQTAPVHF DPLPTPYLDG IRARLTEVKL
     PPKALKSALN SYDQACARWR YSLDESFSQA ARSVSPHNLH LLSTLRFRLY TEQVERWAVQ
     VLQVAEQWRA EMEKQRAHIA ASTDKSKKPR PKFHSEYTPL LELYFRFNAY PTYADRRVLA
     EKTGMLTRQI TVWFQNHRRR AKGPLPRMTP TAKIPLEEFE RERENLARKL LPMLLPPHLR
     PITLGNNKTP DLTTSSRARA LPPAKEDKPP QVTRKTSKKV PKTAHPAPST LVAPSQDTVM
     ADAISTKKTK KAKSKQCADI EMKDSSKPKR RKMKKLPKGV VGTADVAMCI DPPQVPKKNK
     VKPKKSMAFD SQAELAFAQA AYPSPSKYAW VHTRKPQTDA PKAKASSVTS DVARLGKGRP
     GKPSPPASST VPSRRVSTRL NAMRPPYAFP ARYDSAAVPM TFAVAQVTKF TFATDSASFG
     FKPRISTRRP NITSDAMSQL VSSFERLRLL SVELSVSRNP PLPAFEHQRL VDLRVEGLTS
     GEVTALHFTP GAYAARLAVT YIPPRAPLPS TVLDLPRALR ARLVHPMVLP ETVTQPDAFA
     PFIALAERRA RRKARKEKKR QEEKQAKKDK KERKKAGLPH RAPSTVDAPD VSSRASSLDS
     DVSTSARKSS KKSKRQPSSS SRASSVASSG RTPSLSSTSS RRSSGMSMPS TPGPEQSLPI
     VAASDFALGG EEDVSMDADL MAQLFGSDEN ADAVGYDLPM HPEPFTADMI TFTSCADGAL
     GDMTADVNMP NLGQSSIDDM NWTASVGSNA QDPASQESGG DEASHWLDIS FDRPTTTSQI
     NVLGGTYSCE LGGSDNMNAP LDFSDLTFGL DTGADYFSGF NNTIGGTTIM V