ID   MAAZ3_SCHCO             Reviewed;         891 AA.
AC   P37937;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Mating-type protein A-alpha Z3;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UVM 9-4;
RX   PubMed=1353886; DOI=10.1073/pnas.89.15.7169;
RA   Stankis M.M., Specht C.A., Yang H., Giasson L., Ullrich R.C., Novotny C.P.;
RT   "The A alpha mating locus of Schizophyllum commune encodes two dissimilar
RT   multiallelic homeodomain proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:7169-7173(1992).
CC   -!- FUNCTION: Specifies A-alpha-3 mating-type. May regulate the expression
CC       of genes specific to the homokaryotic cell type.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DEVELOPMENTAL STAGE: Expressed constitutively in homokaryons.
CC   -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M97180; AAB01369.1; -; Genomic_DNA.
DR   PIR; B46203; B46203.
DR   AlphaFoldDB; P37937; -.
DR   PRIDE; P37937; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR024333; Mating-type_A-alpha/beta_1_N.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF12731; Mating_N; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..891
FT                   /note="Mating-type protein A-alpha Z3"
FT                   /id="PRO_0000049190"
FT   DNA_BIND        111..189
FT                   /note="Homeobox; TALE-type"
FT   REGION          331..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..671
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          779..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          836..861
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..357
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..399
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..418
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        425..457
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..486
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        544..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..667
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        836..854
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   891 AA;  97306 MW;  E328A0B252E00956 CRC64;
     MLLGEEDIIQ ALSTAQTDFL DALAEGPEAV LTFQTRWGVL RASIDSDLPL QPSTLELSDR
     VSYAIADLAE VLLTQEANNK AIEDDLSNDL VAQFHQYEAF EALEFSENDC EWQENMPPVP
     PFIGACYEWL LQHLHNPYPS NEGRLTPPSS PRSACSILPS LKPALDTCKT FDDIDRWFSA
     ARIRIGWTHI CDTKFGGDKA MMLEAARVMW GSSDEEYEER NFAAGCVSRR SVSPKREEIP
     SYLKSPHDSI AFQARLPEAH EEPAERHCTP PREPPCLDPD VELAFACMET RAHEMYAHRL
     EPSELVDTLS ASALPREAVN DVECQEAIAR AAHEKRQQAR REQRQAKNER DAAQMREEQR
     ASYPSPEPSS DDEGEDEDDE ESTDAYDSEA SDSEDDSDSD TDSHYSQPFA SYARGRTSFL
     SDVSALADDE DEASDDDEDD NVEGDDESEE EEEEEDTTPP PKLAGSKRRA DEDIDGQAEE
     KRLRSASVPH FMYPPSPKSP MVVKRAAHKR PTRRASPSLI RLSPPPAPVT MGPDGVPLGT
     VPSKTTKAPA STSTTKSSTV QVHIPLPAPS SRSIPSSGIK VTGDPTPWVN WDLNAAVPCG
     QSKAEYLDSV GSSRPQRRAS TSSSSSTSSS LSRTPSLTSL SSLSSGSSVS TCETVGTDSS
     EPAVHVQASE TATEAPIKSA AHVHPLFNPD VWSQYNLDAT ADVEFHRGKG RKASSFRPAK
     LLVEAVDLST SPSQHWTPSV RSRTRLAPSV AAPVTSYHHA AGTVTSPIES SFGQGQLTSI
     LSTGPKAGIT RRQTPPAKRR VSPRAQEPVE PSSLVDDIIS SGLVVVCKEI TPVKAPKKDR
     RYAERAERRA SKANSFDSPD TVRARLAEIE QEAARLEAER LSLQRIASVG G