ID   MAAZ4_SCHCO             Reviewed;         940 AA.
AC   P37938;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Mating-type protein A-alpha Z4;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40;
RX   PubMed=1353886; DOI=10.1073/pnas.89.15.7169;
RA   Stankis M.M., Specht C.A., Yang H., Giasson L., Ullrich R.C., Novotny C.P.;
RT   "The A alpha mating locus of Schizophyllum commune encodes two dissimilar
RT   multiallelic homeodomain proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:7169-7173(1992).
CC   -!- FUNCTION: Specifies A-alpha-4 mating-type. May regulate the expression
CC       of genes specific to the homokaryotic cell type.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DEVELOPMENTAL STAGE: Expressed constitutively in homokaryons.
CC   -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M97181; AAB01372.1; -; Genomic_DNA.
DR   PIR; D37271; D37271.
DR   AlphaFoldDB; P37938; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR024333; Mating-type_A-alpha/beta_1_N.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF12731; Mating_N; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..940
FT                   /note="Mating-type protein A-alpha Z4"
FT                   /id="PRO_0000049191"
FT   DNA_BIND        110..182
FT                   /note="Homeobox; TALE-type"
FT   REGION          333..618
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          633..762
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          832..863
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          877..912
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..364
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..402
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..469
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..490
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        511..528
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..599
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..728
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        879..903
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   940 AA;  101856 MW;  4B99CBAEDB39621E CRC64;
     MSLYSAEDIL KWLHHAQAEF LTALAEGDDA LAQFQAQWDR VRACVDCDPT LPSSTLALSH
     AVGISIAQIA EVMLDQEATN HTIEDELTKD LLAGLERHDA SSALADEKTG AELSATPLPP
     YIEPCYRWLV NHLDNPYPTK AIKEELLDQA RQRTSPDVAQ HLALGDIDNW FIAARARMGW
     GDIRRRLFGG SRSLMLQSTR LMWGTEETSR DFTDGCIAKR KGAQPKREEV QPHLRSSHDV
     VAFKIPPKAS PYFLITDSST AACEEPLHPQ SFAALQPDVE FALAHLEVNA KEMYGLEPTE
     LADSLNSSAV DRQFATQDLV AFRAALEAAT AAKQRQARRE QRRAQKDRMD AQRRAEDRKC
     YPSPEPLSAD ELSGTESDED LDDFYASDDA SDDEDDDGED LDTRPSDLMA QMCPQLVATA
     FSKDGSATED EDSNSDDTDE STDDEDEDSD SENDSDSEDE EEEDEEEEEP VKIAGAKRGR
     NDDEEVSPLA KKPRIFSPPV RPRPQAIRVS LPSPAPSSRG STPTSPVSPS PKAKRPAQAT
     SLLASHPMKK REKLQEELRK AGLAPPSAPV LMGPDGVPLG TVRSRSSPSV SSPPSVSVSL
     PLPSRGVPSG GIKVTGDPTP WVNWDLEAHT QAPRDLTAAT KSSAGCSVDA VPLPGKSRSL
     TRSPSISSIS SACSTSSSGS DTDSLFSVTS DATDITEPDE ATTADETTTQ STSASSSRDT
     TSQQKRMPPL SIDPRFDPAL WSKYDLSPPA DGRLHPSDGL RPSAFVPTKL DVRVANLAQN
     PARHWSASKR SPTRASHAAA PIVSYHHATG SIASPAQVAF GEGQLTSVLA TGQKAGNARR
     RTTPVQRRVT PKAQETSEPS SLVDGILSSG LADVCREAPK PAKAPKNDRR YLERRERRLS
     KSSPVDSADT VRTRLAEIEQ EAARLEAERQ SLQRLASVGG