ID   MAB11_COPCI             Reviewed;         681 AA.
AC   P40333;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Mating-type protein beta1-1;
OS   Coprinopsis cinerea (Inky cap fungus) (Hormographiella aspergillata).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Psathyrellaceae; Coprinopsis.
OX   NCBI_TaxID=5346;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=JV6;
RX   PubMed=1582410; DOI=10.1002/j.1460-2075.1992.tb05232.x;
RA   Tymon A.M., Kues U., Richardson W.V.J., Casselton L.A.;
RT   "A fungal mating type protein that regulates sexual and asexual development
RT   contains a POU-related domain.";
RL   EMBO J. 11:1805-1813(1992).
CC   -!- FUNCTION: Has a major regulatory role in sexual and asexual
CC       development. It may bind DNA itself or it may have a role in preventing
CC       DNA-binding of another protein.
CC   -!- SUBUNIT: May dimerize.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DOMAIN: The C-terminal domain has a high percentage of Ser, Pro and Thr
CC       residues.
CC   -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family. {ECO:0000305}.
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DR   EMBL; X62336; CAA44210.1; -; Genomic_DNA.
DR   PIR; S20902; S20902.
DR   AlphaFoldDB; P40333; -.
DR   SMR; P40333; -.
DR   PRIDE; P40333; -.
DR   VEuPathDB; FungiDB:CC1G_01831; -.
DR   VEuPathDB; FungiDB:CC2G_000672; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR024441; Homeodomain1_C.
DR   InterPro; IPR024333; Mating-type_A-alpha/beta_1_N.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF12737; Mating_C; 1.
DR   Pfam; PF12731; Mating_N; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Homeobox; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..681
FT                   /note="Mating-type protein beta1-1"
FT                   /id="PRO_0000049192"
FT   DNA_BIND        165..227
FT                   /note="Homeobox; TALE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          307..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          394..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..373
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..432
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        433..447
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   681 AA;  75057 MW;  9D6420110F6A8B20 CRC64;
     MFAVFWTNLR CLGYNTFTCG VETPTTWGKV GSLDASSSTF TTYRGYPLAM AISAGTPACD
     SPDDNIRRAI NTLRADLSAL LRGESVAYSA FLSACTKFDG FAQSCHGMLS DDTLDLLYSF
     SESLLALSEN MALLETKKEA ESNKFTAEVM AILSDKTSGL DLSDDKNEPT SPTPAYVEPC
     ARWLKDNWYN PYPSGEVRTQ IARQTRTSRK DIDAWFIDAR RRIGWNEVRR KHFENKRVDI
     VRAASIFTGP QSIPAEVDAL PDHIELEFAG ILSRARSLYE EKFSPSKLAV KLDTAVKDMT
     PSLKEQLKND EARRKREAST VGIINQRARH AYPTPERSPA SAAELLASPP SFAIDSDKLP
     SVGRKRRRSL ESDETVSSPL CKRPRSQSVF CELSPVKGLP SPSPSTQDEL LETSAAPSPQ
     PSLLPKLTPT DSARSTGKRK RRLSDGFQYP AAKRPEIRPQ VVSDPFPATS SEHWEQWFRE
     HVLSSPELTL TGDIPPAVTT DAPDSNTPLD IQLFNFPLIP DLPPSVPVVP APTAELNIIE
     PLEVPAVTQV NVDPEATALD HTFSWMASDF PPPLQSTNTF PSSSPFSALD GMSLPFPDTR
     SSAFLPDPSL WSNISDPDLD FSTVFSQPST NSAMTSSIQV PLQPTWLTSR SLSEQEREAK
     RKELEELEAR AQAIRAEISA P