ID   MAB21_CAEBR             Reviewed;         364 AA.
AC   Q9GQ38; A8XSV4; Q60YZ0;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Protein male abnormal 21;
GN   Name=mab-21; ORFNames=CBG18030;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=11500979; DOI=10.1002/dvdy.1161;
RA   Ho S.H., So G.M.K., Chow K.L.;
RT   "Postembryonic expression of Caenorhabditis elegans mab-21 and its
RT   requirement in sensory ray differentiation.";
RL   Dev. Dyn. 221:422-430(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Acts in a cell autonomous fashion to specify the properties
CC       of the sensory ray and non-autonomously in the choice of hypodermal
CC       versus neuroblast cell fate. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mab-21 family. {ECO:0000305}.
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DR   EMBL; AF299247; AAG36973.1; -; Genomic_DNA.
DR   EMBL; HE600963; CAP35557.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q9GQ38; -.
DR   SMR; Q9GQ38; -.
DR   STRING; 6238.CBG18030; -.
DR   EnsemblMetazoa; CBG18030.1; CBG18030.1; WBGene00037527.
DR   WormBase; CBG18030; CBP37045; WBGene00037527; Cbr-mab-21.
DR   eggNOG; KOG3963; Eukaryota.
DR   HOGENOM; CLU_045315_0_0_1; -.
DR   InParanoid; Q9GQ38; -.
DR   OMA; AVDKCKY; -.
DR   OrthoDB; 771781at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0045165; P:cell fate commitment; IEA:EnsemblMetazoa.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:EnsemblMetazoa.
DR   GO; GO:0090597; P:nematode male tail mating organ morphogenesis; IEA:EnsemblMetazoa.
DR   InterPro; IPR024810; Mab-21_dom.
DR   Pfam; PF03281; Mab-21; 1.
DR   SMART; SM01265; Mab-21; 1.
PE   3: Inferred from homology;
KW   Developmental protein; Differentiation; Reference proteome.
FT   CHAIN           1..364
FT                   /note="Protein male abnormal 21"
FT                   /id="PRO_0000312801"
SQ   SEQUENCE   364 AA;  41568 MW;  7202F1DC23049E53 CRC64;
     MLGHNQNVVY QVNTFYNEKV QQRKARVTKN VHRIAKVVQE ILKEVEAQEP RFINTLTETS
     TGRFDGIVVH SPSEYEAVLY LNQMGVFNFV DDGTIQGCAV LKLSDGRKRS MSLWVEFITA
     SGYLSARKIR HRFQNIVAQV LQTPQFSEYC KLLQDNTDVR VRVDDKYTVQ ITCAFRCNGI
     WPRSASHWPL AGLPWPNTAL ANQTKAEGFD LTSRETAITQ HNNPNKQAST MEADAWAMKM
     HGAENMLLTG GRQKTLSILK CLRDAHMDFP GTPVTNYILK TLVLYECEKH CSEYEWEDTN
     IGDRLVGVLL QLVSCLQCRR CAHYFLPSLD LLRAKPTHTI EHSAKLTWHL VRKLMIDPNA
     LQTL