ID   MADL2_XENLA             Reviewed;         302 AA.
AC   Q5XGR0;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Myeloid-associated differentiation marker-like protein 2;
GN   Name=myadml2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MAL family. {ECO:0000305}.
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DR   EMBL; BC084372; AAH84372.1; -; mRNA.
DR   RefSeq; NP_001088324.1; NM_001094855.1.
DR   AlphaFoldDB; Q5XGR0; -.
DR   DNASU; 495162; -.
DR   GeneID; 495162; -.
DR   KEGG; xla:495162; -.
DR   CTD; 495162; -.
DR   Xenbase; XB-GENE-967757; myadml2.L.
DR   OrthoDB; 1056604at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 495162; Expressed in muscle tissue and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008253; Marvel.
DR   Pfam; PF01284; MARVEL; 2.
DR   PROSITE; PS51225; MARVEL; 2.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..302
FT                   /note="Myeloid-associated differentiation marker-like
FT                   protein 2"
FT                   /id="PRO_0000332208"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          13..149
FT                   /note="MARVEL 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT   DOMAIN          154..298
FT                   /note="MARVEL 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
SQ   SEQUENCE   302 AA;  33535 MW;  4283D080A0F8C9F1 CRC64;
     MDSSGGAYLN VDAIWSKVGF VRLLQMLFGC TTFSLVLHRA GFSAAYGTFC VFVWAFCFAL
     TILIVTCELT RLQSCLRSIS WGNFTAAYAM LATLMTLTAA VIYPMYFTSL NCSSSDCSTK
     YFRLAVSVCA ALLFVTYAVE VFLTRAKPGQ PCSYMATASG LLKVVQAFVA CVIFGALASE
     SQYKKFVATQ WCVAVYSFCF GVTMVVVILN ITGRALSLCC PFERFVVIYT VLAILMYISA
     AVIWPVYFFD SKYGSAKRPS RCTWGQCPWD SQLAVTIFTH INLILYIADL IYTQRLRIVA
     QR