MADS1_ORYSJ
ID MADS1_ORYSJ Reviewed; 257 AA.
AC Q10PZ9; B7EGS6; Q3ZES6; Q40700;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=MADS-box transcription factor 1;
DE AltName: Full=OsMADS1;
DE AltName: Full=Protein LEAFY HULL STERILE 1;
DE AltName: Full=Protein SEPALLATA-like;
GN Name=MADS1; Synonyms=LHS1; OrderedLocusNames=Os03g0215400, LOC_Os03g11614;
GN ORFNames=OsJ_09913 {ECO:0000312|EMBL:EEE58586.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC TISSUE=Flower;
RX PubMed=7948920; DOI=10.1007/bf00013751;
RA Chung Y.-Y., Kim S.-R., Finkel D., Yanofsky M.F., An G.;
RT "Early flowering and reduced apical dominance result from ectopic
RT expression of a rice MADS box gene.";
RL Plant Mol. Biol. 26:657-665(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DISRUPTION PHENOTYPE, AND
RP MUTAGENESIS OF ARG-24 AND GLY-27.
RX PubMed=10852934; DOI=10.2307/3871216;
RA Jeon J.-S., Jang S., Lee S., Nam J., Kim C., Lee S.-H., Chung Y.-Y.,
RA Kim S.-R., Lee Y.H., Cho Y.-G., An G.;
RT "Leafy hull sterile1 is a homeotic mutation in a rice MADS box gene
RT affecting rice flower development.";
RL Plant Cell 12:871-884(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [9]
RP INTERACTION WITH MADS6.
RX PubMed=10444103; DOI=10.1104/pp.120.4.1193;
RA Moon Y.-H., Kang H.-G., Jung J.-Y., Jeon J.-S., Sung S.-K., An G.;
RT "Determination of the motif responsible for interaction between the rice
RT APETALA1/AGAMOUS-LIKE9 family proteins using a yeast two-hybrid system.";
RL Plant Physiol. 120:1193-1204(1999).
RN [10]
RP TRANSCRIPTIONAL ACTIVATOR, AND INTERACTION WITH MADS14 AND MADS15.
RX PubMed=11197326; DOI=10.1023/a:1026517111843;
RA Lim J., Moon Y.-H., An G., Jang S.K.;
RT "Two rice MADS domain proteins interact with OsMADS1.";
RL Plant Mol. Biol. 44:513-527(2000).
RN [11]
RP FUNCTION.
RX AGRICOLA=IND22436162; DOI=10.1023/A:1011388620872;
RA Jeon J.-S., Lee S., Nam J., Jung K.-H., Yang W.-S., Yi G.-H., Oh B.-G.,
RA An G.;
RT "Production of transgenic rice plants showing reduced heading date and
RT plant height by ectopic expression of rice MADS-box genes.";
RL Mol. Breed. 6:581-592(2000).
RN [12]
RP FUNCTION, AND DEVELOPMENTAL STAGE.
RX PubMed=11466523; DOI=10.1007/s004270100153;
RA Prasad K., Sriram P., Kumar C.S., Kushalappa K., Vijayraghavan U.;
RT "Ectopic expression of rice OsMADS1 reveals a role in specifying the lemma
RT and palea, grass floral organs analogous to sepals.";
RL Dev. Genes Evol. 211:281-290(2001).
RN [13]
RP FUNCTION.
RX PubMed=16217607; DOI=10.1007/s11103-005-2161-y;
RA Agrawal G.K., Abe K., Yamazaki M., Miyao A., Hirochika H.;
RT "Conservation of the E-function for floral organ identity in rice revealed
RT by the analysis of tissue culture-induced loss-of-function mutants of the
RT OsMADS1 gene.";
RL Plant Mol. Biol. 59:125-135(2005).
CC -!- FUNCTION: Probable transcription factor involved in the development of
CC floral organs. Required for the formation of inner floral organs
CC (lodicules, stamens and carpels, or whorls 2, 3 and 4) and the lemma
CC and palea (whorl 1), which are grass floral organs analogous to sepals.
CC May be involved in the control of flowering time. Seems to act as
CC transcriptional activator. May act upstream of the auxin-responsive
CC protein GH3.8. {ECO:0000269|PubMed:10852934,
CC ECO:0000269|PubMed:11466523, ECO:0000269|PubMed:16217607,
CC ECO:0000269|PubMed:7948920, ECO:0000269|Ref.11}.
CC -!- SUBUNIT: May interact with the K-box of MADS6, MADS14 and MADS15.
CC -!- INTERACTION:
CC Q10PZ9; Q10CQ1: MADS14; NbExp=4; IntAct=EBI-627957, EBI-627890;
CC Q10PZ9; Q6Q9I2: MADS15; NbExp=4; IntAct=EBI-627957, EBI-627918;
CC Q10PZ9; Q6EU39: MADS6; NbExp=4; IntAct=EBI-627957, EBI-627980;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in lemmas, paleas and pistils. Weakly
CC expressed in carpels. {ECO:0000269|PubMed:7948920}.
CC -!- DEVELOPMENTAL STAGE: Expressed at early stage of flower development in
CC floral meristem, and at later stage in lemma, palea and carpel
CC primordia. {ECO:0000269|PubMed:11466523}.
CC -!- DISRUPTION PHENOTYPE: Homeotic transformation of lodicules, stamens and
CC carpels into lemma- and palea-like structures.
CC {ECO:0000269|PubMed:10852934}.
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DR EMBL; L34271; AAA66187.1; -; mRNA.
DR EMBL; AF204063; AAG35652.1; -; Genomic_DNA.
DR EMBL; AC105732; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC135158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DP000009; ABF94637.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF11290.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS82963.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE58586.1; -; Genomic_DNA.
DR EMBL; AK069728; BAG91573.1; -; mRNA.
DR PIR; S53306; S53306.
DR RefSeq; XP_015628585.1; XM_015773099.1.
DR AlphaFoldDB; Q10PZ9; -.
DR SMR; Q10PZ9; -.
DR BioGRID; 801096; 1.
DR IntAct; Q10PZ9; 4.
DR STRING; 4530.OS03T0215400-01; -.
DR PaxDb; Q10PZ9; -.
DR PRIDE; Q10PZ9; -.
DR EnsemblPlants; Os03t0215400-01; Os03t0215400-01; Os03g0215400.
DR GeneID; 4332059; -.
DR Gramene; Os03t0215400-01; Os03t0215400-01; Os03g0215400.
DR KEGG; osa:4332059; -.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_2_1; -.
DR InParanoid; Q10PZ9; -.
DR OMA; GFFPGWT; -.
DR OrthoDB; 1138027at2759; -.
DR PlantReactome; R-OSA-9608931; Floral bracts development.
DR PlantReactome; R-OSA-9609102; Flower development.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q10PZ9; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; TAS:AgBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; TAS:AgBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0008134; F:transcription factor binding; TAS:AgBase.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0010582; P:floral meristem determinacy; TAS:AgBase.
DR GO; GO:0010022; P:meristem determinacy; IGI:AgBase.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0048509; P:regulation of meristem development; IGI:AgBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0010093; P:specification of floral organ identity; IMP:AgBase.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 1: Evidence at protein level;
KW Activator; Developmental protein; Differentiation; DNA-binding; Flowering;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..257
FT /note="MADS-box transcription factor 1"
FT /id="PRO_0000229892"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 85..175
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT MUTAGEN 24
FT /note="R->C: In lhs1; abnormal growth of spikelets and
FT sterile flowers; when associated with D-27."
FT /evidence="ECO:0000269|PubMed:10852934"
FT MUTAGEN 27
FT /note="G->D: In lhs1; abnormal growth of spikelets and
FT sterile flowers; when associated with C-24."
FT /evidence="ECO:0000269|PubMed:10852934"
SQ SEQUENCE 257 AA; 29528 MW; 70A3DAEED355A37C CRC64;
MGRGKVELKR IENKISRQVT FAKRRNGLLK KAYELSLLCD AEVALIIFSG RGRLFEFSSS
SCMYKTLERY RSCNYNSQDA AAPENEINYQ EYLKLKTRVE FLQTTQRNIL GEDLGPLSMK
ELEQLENQIE VSLKQIRSRK NQALLDQLFD LKSKEQQLQD LNKDLRKKLQ ETSAENVLHM
SWQDGGGHSG SSTVLADQPH HHQGLLHPHP DQGDHSLQIG YHHPHAHHHQ AYMDHLSNEA
ADMVAHHPNE HIPSGWI
