MADS2_ORYSJ
ID MADS2_ORYSJ Reviewed; 209 AA.
AC Q40702; Q0JH52; Q6Q9H8; Q7F2L5; Q9AUJ1;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=MADS-box transcription factor 2;
DE AltName: Full=NMADS1;
DE AltName: Full=OsMADS2;
DE AltName: Full=RMADS219;
GN Name=MADS2; Synonyms=MADS; OrderedLocusNames=Os01g0883100, LOC_Os01g66030;
GN ORFNames=B1065E10.30, OsJ_04312 {ECO:0000312|EMBL:EEE55765.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, AND
RP DEVELOPMENTAL STAGE.
RC TISSUE=Immature flower;
RA Chung Y.-Y., Kim S.-R., Kang H.-G., Noh Y.-S., Park M.C., Finkel D., An G.;
RT "Characterization of two rice MADS box genes homologous to GLOBOSA.";
RL Plant Sci. 109:45-56(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Yoon U.-H., Hahn J.-H., Eun M.-Y.;
RT "Molecular cloning of MADS gene in rice.";
RL Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RA Yao Q., Peng R., Xiong A.;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [7]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [9]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [10]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 8-164 (ISOFORM 2).
RA Yuan Z., Qian X., Liu J., Liu J., Qian M., Yang J.;
RT "Cloning and characterization of two cDNAs encoding rice MADS box
RT protein.";
RL Prog. Nat. Sci. 10:357-363(2000).
RN [11]
RP DEVELOPMENTAL STAGE.
RX PubMed=10945340; DOI=10.1093/pcp/41.6.710;
RA Kyozuka J., Kobayashi T., Morita M., Shimamoto K.;
RT "Spatially and temporally regulated expression of rice MADS box genes with
RT similarity to Arabidopsis class A, B and C genes.";
RL Plant Cell Physiol. 41:710-718(2000).
RN [12]
RP FUNCTION.
RX PubMed=14704206; DOI=10.1093/genetics/165.4.2301;
RA Prasad K., Vijayraghavan U.;
RT "Double-stranded RNA interference of a rice PI/GLO paralog, OsMADS2,
RT uncovers its second-whorl-specific function in floral organ patterning.";
RL Genetics 165:2301-2305(2003).
CC -!- FUNCTION: Probable transcription factor involved in the development of
CC floral organs. B-class protein required for normal development of
CC lodicules (whorl 2). {ECO:0000269|PubMed:14704206}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q40702-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q40702-2; Sequence=VSP_015392, VSP_015393;
CC -!- TISSUE SPECIFICITY: Highly expressed in anthers and carpels. Expressed
CC in pollen, tapetum and stigma. {ECO:0000269|Ref.1}.
CC -!- DEVELOPMENTAL STAGE: Expressed in lodicules and stamens from early to
CC late stage of flower development. {ECO:0000269|PubMed:10945340,
CC ECO:0000269|Ref.1}.
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DR EMBL; L37526; AAB52709.1; -; mRNA.
DR EMBL; AF254557; AAK17066.1; -; Genomic_DNA.
DR EMBL; AY551924; AAS59830.1; -; mRNA.
DR EMBL; AP003561; BAB90370.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF06926.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS75578.1; -; Genomic_DNA.
DR EMBL; CM000138; EEE55765.1; -; Genomic_DNA.
DR EMBL; AK070894; BAG92196.1; -; mRNA.
DR EMBL; AF095645; AAK26240.1; -; mRNA.
DR PIR; T03894; T03894.
DR RefSeq; XP_015623988.1; XM_015768502.1. [Q40702-1]
DR AlphaFoldDB; Q40702; -.
DR SMR; Q40702; -.
DR IntAct; Q40702; 1.
DR STRING; 4530.OS01T0883100-01; -.
DR PaxDb; Q40702; -.
DR PRIDE; Q40702; -.
DR EnsemblPlants; Os01t0883100-01; Os01t0883100-01; Os01g0883100. [Q40702-1]
DR GeneID; 4325001; -.
DR Gramene; Os01t0883100-01; Os01t0883100-01; Os01g0883100. [Q40702-1]
DR KEGG; osa:4325001; -.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_4_1; -.
DR InParanoid; Q40702; -.
DR OMA; KLMEHWE; -.
DR OrthoDB; 1276495at2759; -.
DR PlantReactome; R-OSA-9609102; Flower development.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q40702; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0010097; P:specification of stamen identity; TAS:AgBase.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; Developmental protein; Differentiation;
KW DNA-binding; Flowering; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..209
FT /note="MADS-box transcription factor 2"
FT /id="PRO_0000199499"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 84..170
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT VAR_SEQ 146..164
FT /note="HVRTDKMLEDENKLLAFKL -> IRCWKTRTSCWLSNCTSKI (in
FT isoform 2)"
FT /evidence="ECO:0000303|Ref.10"
FT /id="VSP_015392"
FT VAR_SEQ 165..209
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.10"
FT /id="VSP_015393"
FT CONFLICT 1
FT /note="M -> MM (in Ref. 3; AAS59830)"
FT /evidence="ECO:0000305"
FT CONFLICT 10
FT /note="R -> S (in Ref. 10; AAK26240)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 209 AA; 24158 MW; B2AFE95E69EB0E33 CRC64;
MGRGKIEIKR IENSTNRQVT FSKRRSGILK KAREISVLCD AEVGVVIFSS AGKLYDYCSP
KTSLSRILEK YQTNSGKILW DEKHKSLSAE IDRIKKENDN MQIELRHLKG EDLNSLQPKE
LIMIEEALDN GIVNVNDKLM DHWERHVRTD KMLEDENKLL AFKLHQQDIA LSGSMRDLEL
GYHPDRDFAA QMPITFRVQP SHPNLQENN
