MADS4_ORYSJ
ID MADS4_ORYSJ Reviewed; 215 AA.
AC Q40703; Q0DI19; Q60EP4;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 3.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=MADS-box transcription factor 4;
DE AltName: Full=OsMADS4;
GN Name=MADS4; OrderedLocusNames=Os05g0423400, LOC_Os05g34940;
GN ORFNames=OJ1212_B02.5;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND TISSUE SPECIFICITY.
RC TISSUE=Immature flower;
RA Chung Y.-Y., Kim S.-R., Kang H.-G., Noh Y.-S., Park M.C., Finkel D., An G.;
RT "Characterization of two rice MADS box genes homologous to GLOBOSA.";
RL Plant Sci. 109:45-56(1995).
RN [2]
RP SEQUENCE REVISION.
RA An G.;
RL Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP FUNCTION.
RX PubMed=9869408; DOI=10.1023/a:1006051911291;
RA Kang H.-G., Jeon J.-S., Lee S., An G.;
RT "Identification of class B and class C floral organ identity genes from
RT rice plants.";
RL Plant Mol. Biol. 38:1021-1029(1998).
RN [9]
RP TISSUE SPECIFICITY, AND INTERACTION WITH MADS16.
RX PubMed=10394955; DOI=10.1023/a:1026429922616;
RA Moon Y.-H., Jung J.-Y., Kang H.-G., An G.;
RT "Identification of a rice APETALA3 homologue by yeast two-hybrid
RT screening.";
RL Plant Mol. Biol. 40:167-177(1999).
RN [10]
RP TISSUE SPECIFICITY, AND INTERACTION WITH MADS16.
RX PubMed=12905025; DOI=10.1007/s00425-003-1066-8;
RA Lee S., Jeon J.-S., An K., Moon Y.-H., Lee S.-H., Chung Y.-Y., An G.;
RT "Alteration of floral organ identity in rice through ectopic expression of
RT OsMADS16.";
RL Planta 217:904-911(2003).
CC -!- FUNCTION: Probable transcription factor involved in the development of
CC floral organs. B-class protein required for normal development of
CC lodicules and stamens (whorls 2 and 3). May function as a heterodimer
CC with MADS16. {ECO:0000269|PubMed:9869408}.
CC -!- SUBUNIT: May interact with the K-box of MADS16.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=2;
CC IsoId=Q40703-1; Sequence=Displayed;
CC Name=1;
CC IsoId=Q40703-2; Sequence=VSP_015394;
CC -!- TISSUE SPECIFICITY: Highly expressed in lodicules, at intermediate
CC levels in stamens, and weakly in carpels. Expressed in pollen.
CC {ECO:0000269|PubMed:10394955, ECO:0000269|PubMed:12905025,
CC ECO:0000269|Ref.1}.
CC -!- MISCELLANEOUS: Antisense inhibition of MADS4 expression transforms
CC lodicules and stamens into palea/lemma-like and carpel-like organs,
CC respectively.
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
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DR EMBL; L37527; AAC05723.1; -; mRNA.
DR EMBL; AC109595; AAV24770.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF17504.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS94096.1; -; Genomic_DNA.
DR EMBL; AK100233; BAG94502.1; -; mRNA.
DR PIR; T03902; T03902.
DR AlphaFoldDB; Q40703; -.
DR SMR; Q40703; -.
DR STRING; 4530.OS05T0423400-01; -.
DR PaxDb; Q40703; -.
DR PRIDE; Q40703; -.
DR EnsemblPlants; Os05t0423400-01; Os05t0423400-01; Os05g0423400. [Q40703-1]
DR Gramene; Os05t0423400-01; Os05t0423400-01; Os05g0423400. [Q40703-1]
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_4_1; -.
DR InParanoid; Q40703; -.
DR OMA; LVHMKGE; -.
DR PlantReactome; R-OSA-9609102; Flower development.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR Genevisible; Q40703; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0010093; P:specification of floral organ identity; IMP:UniProtKB.
DR GO; GO:0010097; P:specification of stamen identity; TAS:AgBase.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 1: Evidence at protein level;
KW Activator; Alternative splicing; Developmental protein; Differentiation;
KW DNA-binding; Flowering; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..215
FT /note="MADS-box transcription factor 4"
FT /id="PRO_0000199500"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 89..175
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT VAR_SEQ 64..68
FT /note="Missing (in isoform 1)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_015394"
FT CONFLICT 26
FT /note="A -> S (in Ref. 1; AAC05723)"
FT /evidence="ECO:0000305"
FT CONFLICT 41
FT /note="A -> R (in Ref. 1; AAC05723)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 215 AA; 24908 MW; FD24ED8F4ED1F213 CRC64;
MGRGKIEIKR IENSTNRQVT FSKRRAGILK KAREIGVLCD AEVGVVIFSS AGKLSDYCTP
KTTSVFPPLS RILEKYQTNS GKILWDEKHK SLSAEIDRVK KENDNMQIEL RHMKGEDLNS
LQPKELIAIE EALNNGQANL RDKMMDHWRM HKRNEKMLED EHKMLAFRVH QQEVELSGGI
RELELGYHHD DRDFAASMPF TFRVQPSHPN LQQEK
