MADS4_VITVI
ID MADS4_VITVI Reviewed; 242 AA.
AC Q8LLR0; F6HGC4;
DT 05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT 05-JUN-2019, sequence version 2.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Agamous-like MADS-box protein MADS4 {ECO:0000305};
DE AltName: Full=MADS-box protein 4 {ECO:0000303|Ref.1};
DE Short=VvMADS4 {ECO:0000303|Ref.1};
DE AltName: Full=SEPALLATA homolog 3 {ECO:0000305};
DE Short=VvSEP3 {ECO:0000303|PubMed:18997115};
DE Short=VviSEP3 {ECO:0000303|PubMed:26818751};
GN Name=MADS4 {ECO:0000303|Ref.1};
GN OrderedLocusNames=VIT_01s0010g03900 {ECO:0000312|EMBL:CBI27678.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND TISSUE SPECIFICITY.
RC STRAIN=cv. Cabernet Sauvignon;
RX DOI=10.1016/S0168-9452(02)00034-1;
RA Boss P.K., Sensi E., Hua C., Davies C., Thomas M.R.;
RT "Cloning and characterization of grapevine (Vitis vinifera L.) MADS-box
RT genes expressed during inflorescence and berry development.";
RL Plant Sci. 162:887-895(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024;
RX PubMed=17721507; DOI=10.1038/nature06148;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
RN [3]
RP GENE FAMILY.
RX PubMed=18997115; DOI=10.1104/pp.108.131052;
RA Diaz-Riquelme J., Lijavetzky D., Martinez-Zapater J.M., Carmona M.J.;
RT "Genome-wide analysis of MIKCC-type MADS box genes in grapevine.";
RL Plant Physiol. 149:354-369(2009).
RN [4]
RP GENE FAMILY.
RX PubMed=26818751; DOI=10.1186/s12864-016-2398-7;
RA Grimplet J., Martinez-Zapater J.M., Carmona M.J.;
RT "Structural and functional annotation of the MADS-box transcription factor
RT family in grapevine.";
RL BMC Genomics 17:80-80(2016).
CC -!- FUNCTION: Probable transcription factor involved in flower development.
CC {ECO:0000250|UniProtKB:Q0HA25}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8LLR0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8LLR0-2; Sequence=VSP_060175, VSP_060176;
CC -!- TISSUE SPECIFICITY: Expressed in flowers and seeds.
CC {ECO:0000269|Ref.1}.
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DR EMBL; AF373603; AAM21344.1; -; mRNA.
DR EMBL; FN597015; CBI27678.3; -; Genomic_DNA.
DR RefSeq; NP_001268114.1; NM_001281185.1.
DR AlphaFoldDB; Q8LLR0; -.
DR SMR; Q8LLR0; -.
DR STRING; 29760.VIT_01s0010g03900.t01; -.
DR EnsemblPlants; Vitvi01g01677_t001; Vitvi01g01677_P001; Vitvi01g01677. [Q8LLR0-1]
DR GeneID; 100232869; -.
DR Gramene; Vitvi01g01677_t001; Vitvi01g01677_P001; Vitvi01g01677. [Q8LLR0-1]
DR KEGG; vvi:100232869; -.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_2_1; -.
DR OMA; YQGQQDH; -.
DR OrthoDB; 1064537at2759; -.
DR Proteomes; UP000009183; Chromosome 1.
DR ExpressionAtlas; Q8LLR0; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Flowering; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..242
FT /note="Agamous-like MADS-box protein MADS4"
FT /id="PRO_0000447292"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 89..185
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT VAR_SEQ 219..221
FT /note="YQP -> PIQ (in isoform 2)"
FT /id="VSP_060175"
FT VAR_SEQ 222..242
FT /note="Missing (in isoform 2)"
FT /id="VSP_060176"
FT CONFLICT 108
FT /note="R -> L (in Ref. 1; AAM21344)"
SQ SEQUENCE 242 AA; 27711 MW; 700C95DB8A492A90 CRC64;
MGRGRVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEVALIIFSN RGKLYEFCSS
SSMLKTLERY QKCNYGAPET NVSTREALEL SSQQEYLKLK ARYEALQRSQ RNLLGEDLGP
LSTKELESLE RQLDVSLKQI RSTRTQYMLD QLTDLQRKEH MLNEANKTLK QRLLEGTQVN
QLQWNPNAQD VGYGRQQAQP QGDGFFHPLE CEPTLQIGYQ PDPITVAAAG PSVNNYMPGW
LP
