ID   MAF1_CANGA              Reviewed;         391 AA.
AC   Q6FIZ7;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Repressor of RNA polymerase III transcription MAF1;
GN   Name=MAF1; OrderedLocusNames=CAGL0M10351g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Mediator of diverse signals that repress RNA polymerase III
CC       transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAF1 family. {ECO:0000305}.
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DR   EMBL; CR380959; CAG62775.1; -; Genomic_DNA.
DR   RefSeq; XP_449797.1; XM_449797.1.
DR   AlphaFoldDB; Q6FIZ7; -.
DR   STRING; 5478.XP_449797.1; -.
DR   EnsemblFungi; CAG62775; CAG62775; CAGL0M10351g.
DR   GeneID; 2891361; -.
DR   KEGG; cgr:CAGL0M10351g; -.
DR   CGD; CAL0136927; CAGL0M10351g.
DR   VEuPathDB; FungiDB:CAGL0M10351g; -.
DR   eggNOG; KOG3104; Eukaryota.
DR   HOGENOM; CLU_037043_2_1_1; -.
DR   InParanoid; Q6FIZ7; -.
DR   OMA; INIGPFG; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0000994; F:RNA polymerase III core binding; IEA:EnsemblFungi.
DR   GO; GO:0016480; P:negative regulation of transcription by RNA polymerase III; IEA:EnsemblFungi.
DR   GO; GO:0061587; P:transfer RNA gene-mediated silencing; IEA:EnsemblFungi.
DR   Gene3D; 3.40.1000.50; -; 1.
DR   InterPro; IPR015257; Maf1.
DR   InterPro; IPR038564; Maf1_sf.
DR   PANTHER; PTHR22504; PTHR22504; 1.
DR   Pfam; PF09174; Maf1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..391
FT                   /note="Repressor of RNA polymerase III transcription MAF1"
FT                   /id="PRO_0000213971"
FT   REGION          75..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          159..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          348..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..189
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   391 AA;  44346 MW;  FE06EFCC00134295 CRC64;
     MKFIDELDIE RVNQVLNFET IDCKIVGGCD IFTTKAVASD RKLYKTIDHH LDTILQDNES
     YNLALQQQIA LDAEDKNERS MSPGGQRRDS SSFWEQKRRM SVSDSPIYLQ HINGNLNESN
     GAQGEIVADL VPPIIKTSKL NDHNLKELVS NYEAGYSSSS SVESLTHKNK ERRTSSLSST
     GGKVDKLRAD SSTANDITAR SVLNDTSRTL NLGPFGPINE PSSRRTFAYL IAILNASYPD
     HDFSLLEPTD FKRSSIKSFI AKFENSMYSL GRKPEEWIWE VINSHMTLSD CVLYQYCPTQ
     SFLDDEPGHL WSLIGFFFNK KRKRVAYVYL LASRLQLAVN NAIGTPDEMQ NEDGTFRNNN
     TTSFDNNNTQ FEGEYDLTYE ENAIVDDDDE E