ID   MAFA2_NEIMA             Reviewed;         313 AA.
AC   A1ITU2;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Adhesin MafA 2;
DE   Flags: Precursor;
GN   Name=mafA2; OrderedLocusNames=NMA2112;
OS   Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS   Z2491).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122587;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15465 / Z2491;
RX   PubMed=10761919; DOI=10.1038/35006655;
RA   Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA   Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA   Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA   Barrell B.G.;
RT   "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT   Z2491.";
RL   Nature 404:502-506(2000).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MafA family. {ECO:0000305}.
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DR   EMBL; AL157959; CAM09211.1; -; Genomic_DNA.
DR   PIR; G81782; G81782.
DR   RefSeq; WP_002245878.1; NC_003116.1.
DR   AlphaFoldDB; A1ITU2; -.
DR   PRIDE; A1ITU2; -.
DR   EnsemblBacteria; CAM09211; CAM09211; NMA2112.
DR   KEGG; nma:NMA2112; -.
DR   HOGENOM; CLU_985210_0_0_4; -.
DR   OMA; TKNNGRK; -.
DR   BioCyc; NMEN122587:NMA_RS10750-MON; -.
DR   Proteomes; UP000000626; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell adhesion; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW   Signal; Virulence.
FT   SIGNAL          1..14
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           15..313
FT                   /note="Adhesin MafA 2"
FT                   /id="PRO_0000344486"
FT   REGION          282..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..313
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           15
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           15
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   313 AA;  33929 MW;  DFB76F2C537C5D7D CRC64;
     MKTLLLLIPL VLTACGTLTG IPAHGGGKRF AVEQELVAAS SRAAVKEMDL SALKGRKAAL
     YVSVMGDQGS GNISGGRYSI DALIRGGYHN NPESATQYSY PAYDTTATTK SDALSSVTTS
     TSLLNAPAAA LTKNSGRKGE RSAGLSVNGT GDYRNETLLA NPRDVSFLTN LIQTVFYLRG
     IEVVPPEYAD TDVFVTVDVF GTVRSRTELH LYNAETLKAQ TKLEYFAVDR DSRKLLIAPK
     TAAYESQYQE QYALWMGPYS VGKTVKASDR LMVDFSDITP YGDTTAQNRP DFKQNNGKKP
     DVGNEVIRRR KGG