ID   MAFA2_NEIMF             Reviewed;         313 AA.
AC   A1KVQ6;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Adhesin MafA 2;
DE   Flags: Precursor;
GN   Name=mafA2; OrderedLocusNames=NMC1789;
OS   Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM
OS   15464 / FAM18).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=272831;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700532 / DSM 15464 / FAM18;
RX   PubMed=17305430; DOI=10.1371/journal.pgen.0030023;
RA   Bentley S.D., Vernikos G.S., Snyder L.A.S., Churcher C., Arrowsmith C.,
RA   Chillingworth T., Cronin A., Davis P.H., Holroyd N.E., Jagels K.,
RA   Maddison M., Moule S., Rabbinowitsch E., Sharp S., Unwin L., Whitehead S.,
RA   Quail M.A., Achtman M., Barrell B.G., Saunders N.J., Parkhill J.;
RT   "Meningococcal genetic variation mechanisms viewed through comparative
RT   analysis of serogroup C strain FAM18.";
RL   PLoS Genet. 3:230-240(2007).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MafA family. {ECO:0000305}.
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DR   EMBL; AM421808; CAM10960.1; -; Genomic_DNA.
DR   RefSeq; WP_011798990.1; NC_008767.1.
DR   AlphaFoldDB; A1KVQ6; -.
DR   EnsemblBacteria; CAM10960; CAM10960; NMC1789.
DR   KEGG; nmc:NMC1789; -.
DR   HOGENOM; CLU_985210_0_0_4; -.
DR   OMA; TKNNGRK; -.
DR   OrthoDB; 646498at2; -.
DR   Proteomes; UP000002286; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell adhesion; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW   Signal; Virulence.
FT   SIGNAL          1..14
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           15..313
FT                   /note="Adhesin MafA 2"
FT                   /id="PRO_0000344491"
FT   REGION          282..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..313
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           15
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           15
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   313 AA;  33942 MW;  826DDDAE669FBE1C CRC64;
     MKTLLLLIPL VLTACGTLTG IPAHGGGKRF AVEQELVAAS SRAAVKEMDL SALKGRKAAL
     YVSVMGDQGS GNISGGRYSI DALIRGGYHN NPESATQYSY PAYDTTATTK ADALSSVTTS
     TSLLNAPAAA LTRNSGRKGE RSAGLSVNGT GDYRNETLLA NPRDVSFLTN LIQTVFYLRG
     IEVVPPEYAD TDVFVTVDVF GTVRSRTELH LYNAETLKAQ TKLEYFAVDR DSRKLLIAPE
     TAAYESQYQE QYALWMGPYS VGKTVKASDR LMVDFSDITP YGDTTAQNRP DFKQNNGKKP
     DVGNEVIRRR KGG