ID   MAF_AVIS4               Reviewed;         369 AA.
AC   P23091;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=Transforming protein Maf;
GN   Name=V-MAF;
OS   Avian musculoaponeurotic fibrosarcoma virus AS42.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus;
OC   unclassified Alpharetrovirus.
OX   NCBI_TaxID=11873;
OH   NCBI_TaxID=8976; Galliformes.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2554284; DOI=10.1073/pnas.86.20.7711;
RA   Nishizawa M., Kataoka K., Goto N., Fujiwara K.T., Kawai S.;
RT   "v-maf, a viral oncogene that encodes a 'leucine zipper' motif.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:7711-7715(1989).
CC   -!- FUNCTION: Might be a transcriptional trans-activator.
CC   -!- SUBCELLULAR LOCATION: Host nucleus.
CC   -!- MISCELLANEOUS: This protein is synthesized as an Env-Maf polyprotein.
CC   -!- SIMILARITY: Belongs to the bZIP family. Maf subfamily. {ECO:0000305}.
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DR   EMBL; M26769; AAA42377.1; -; Genomic_RNA.
DR   PIR; B33975; TVFVAF.
DR   SMR; P23091; -.
DR   MINT; P23091; -.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR004826; bZIP_Maf.
DR   InterPro; IPR046347; bZIP_sf.
DR   InterPro; IPR028573; Maf/V-MAF.
DR   InterPro; IPR013592; Maf_TF_N.
DR   InterPro; IPR008917; TF_DNA-bd_sf.
DR   InterPro; IPR024874; Transcription_factor_Maf_fam.
DR   PANTHER; PTHR10129; PTHR10129; 1.
DR   PANTHER; PTHR10129:SF9; PTHR10129:SF9; 1.
DR   Pfam; PF03131; bZIP_Maf; 1.
DR   Pfam; PF08383; Maf_N; 1.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF47454; SSF47454; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
DR   PROSITE; PS50217; BZIP; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host nucleus; Oncogene; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..369
FT                   /note="Transforming protein Maf"
FT                   /id="PRO_0000076506"
FT   DOMAIN          274..337
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          57..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          169..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..299
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          302..323
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          341..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   369 AA;  38892 MW;  F386B220ACE50FF6 CRC64;
     MASELAMSGS DLPTSPLAME YVNDFDLMKF EVKKEPVETD RIISQCGRLI AGGSLSSTPM
     STPCSSVPPS PSFSAPSPGS GTDQKTHLED YYWMTGYPQQ LNPEALGFSP EDAVEALINS
     SHHPLPGAFD GYARGQQLAA AAGGSVPAEE MGSAAAVVSA VIAAAAAQGG APHYHHHHHH
     PHHGGGGGGG GHPHGAAPGS APPSSASSSA AGSGGGGGGG GGGAGGLHHP HHGGGGGGGG
     LHFDDRFSDE QLVTMSMREL NRQLRGVSKE EVIRLKQKRR TLKNRGYAQS CRFKRVQQRH
     VLESEKNQLL QQVEHLKQEI SRLVRERDAY KEKYEKLVSN GFRENGSSSD NPSSPEFFMY
     PRESSTTVM