MAG2L_ARATH
ID MAG2L_ARATH Reviewed; 804 AA.
AC Q8GXP1; Q9SJF2;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=RINT1-like protein MAG2L {ECO:0000305};
DE AltName: Full=Protein MAIGO 2 homolog {ECO:0000305};
DE AltName: Full=Protein MAIGO 2-like {ECO:0000303|PubMed:23025793};
GN Name=MAG2L {ECO:0000303|PubMed:23025793};
GN OrderedLocusNames=At1g08400 {ECO:0000312|Araport:AT1G08400};
GN ORFNames=T27G7.8 {ECO:0000312|EMBL:AAF22903.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAC42753.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=23025793; DOI=10.1111/j.1399-3054.2012.01704.x;
RA Zhao P., Liu F., Zhang B., Liu X., Wang B., Gong J., Yu G., Ma M., Lu Y.,
RA Sun J., Wang Z., Jia P., Liu H.;
RT "MAIGO2 is involved in abscisic acid-mediated response to abiotic stresses
RT and Golgi-to-ER retrograde transport.";
RL Physiol. Plantarum 148:246-260(2013).
CC -!- FUNCTION: May function in the anterograde transport of protein from the
CC endoplasmic reticulum (ER) to the Golgi complex and in the retrograde
CC transport from the Golgi complex to the ER.
CC {ECO:0000269|PubMed:23025793}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q9STU3}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:Q9STU3}.
CC -!- TISSUE SPECIFICITY: Highly expressed in dry seeds. Expressed at low
CC levels in roots, rosette and cauline leaves, stems and flowers.
CC {ECO:0000269|PubMed:23025793}.
CC -!- INDUCTION: By salt and osmotic stresses. {ECO:0000269|PubMed:23025793}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:23025793}.
CC -!- SIMILARITY: Belongs to the RINT1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF22903.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006932; AAF22903.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28285.1; -; Genomic_DNA.
DR EMBL; BT006154; AAP04139.1; -; mRNA.
DR EMBL; AK118127; BAC42753.1; -; mRNA.
DR PIR; D86217; D86217.
DR RefSeq; NP_172316.2; NM_100713.3.
DR AlphaFoldDB; Q8GXP1; -.
DR BioGRID; 22601; 1.
DR STRING; 3702.AT1G08400.1; -.
DR PaxDb; Q8GXP1; -.
DR PRIDE; Q8GXP1; -.
DR ProteomicsDB; 238626; -.
DR EnsemblPlants; AT1G08400.1; AT1G08400.1; AT1G08400.
DR GeneID; 837360; -.
DR Gramene; AT1G08400.1; AT1G08400.1; AT1G08400.
DR KEGG; ath:AT1G08400; -.
DR Araport; AT1G08400; -.
DR TAIR; locus:2201771; AT1G08400.
DR eggNOG; KOG2218; Eukaryota.
DR HOGENOM; CLU_384326_0_0_1; -.
DR InParanoid; Q8GXP1; -.
DR OMA; WMHLNDL; -.
DR OrthoDB; 1393136at2759; -.
DR PhylomeDB; Q8GXP1; -.
DR PRO; PR:Q8GXP1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8GXP1; baseline and differential.
DR GO; GO:0030142; C:COPI-coated Golgi to ER transport vesicle; TAS:UniProtKB.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; TAS:UniProtKB.
DR GO; GO:0070939; C:Dsl1/NZR complex; IBA:GO_Central.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR InterPro; IPR007528; RINT1_Tip20.
DR PANTHER; PTHR13520; PTHR13520; 1.
DR Pfam; PF04437; RINT1_TIP1; 2.
DR PROSITE; PS51386; RINT1_TIP20; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; ER-Golgi transport; Membrane; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..804
FT /note="RINT1-like protein MAG2L"
FT /id="PRO_0000430531"
FT DOMAIN 205..804
FT /note="RINT1/TIP20"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00717"
SQ SEQUENCE 804 AA; 92352 MW; 8F19B2904AD17837 CRC64;
MLPMEHPLPL SFVLPNPATL PGLALGFIDG NFVDLQDLLL RASTLTSNLN HDCSDLNDRL
LHLRTDLTKH AVSWISTSLS AKVSLEDLRL NLESLLCLPT DSVGKQTNWE LQQVVEELCR
IQNRRKYFVT ALKLESLVGD LEDSVFHPIS KRKGSTLQDL ALKQERFSHA IKTMNEIEEI
LGDVTRHHSR WRRLVDSVDS RVDKSLSVLR PQIIADHRAF LSSLGWPPKL ATSKVEHGEV
DSIPNPLLLM QGDKKESYSQ SFLLLCGLQQ HNTQKEKRKK LNMTKETDND GLWATDELVK
PVASRMEYHF LKWAEQPEFI FELVYKVTRD FADGVDDFLQ PLIDRAMLVS CSAKEAWVSA
MVQMLSGFLE KKVFPGLIDM YKEKHMKSEG ISSWFHLVDQ MVTFDKRMQS FVNTDTCLSY
EGSSTAFSQG ISVMGLFCKK PEWLKTWGKI ELKDAYRKSK EDIKNEKAWV IDSERTRLGN
ESNSQSAKYV LSTREDYKAP LVADSFLNRT WRLIDHGLSL PAILPRIQFI RATATRFLWC
IFKILLLEFK KTDLSHYGLS EDTLIQACGP VNAARYLESK LREWSDDLVF VEMWAAETSV
KVDRKPEVSC QGCFFGEELK SLVELETNWL MEIITVFLHQ FDNLCSDHFH NNAVSWDEDV
ITSSSNLTVS QGVAEALDNL RRHLCVLHLN MNPKDFLDLW RNLAEGLDHY VSRKFFSGEP
VLRRQKFDRF EVDAEALLTV LKPYCVRPGA FFPRVREILR LLRMHEEEKA RLRGALSRSG
NTCLKLFGIS NLSPQLVEQF CRSY
