MAGAB_HUMAN
ID MAGAB_HUMAN Reviewed; 429 AA.
AC P43364; Q5ETU4; Q6ZRZ5;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 2.
DT 03-AUG-2022, entry version 170.
DE RecName: Full=Melanoma-associated antigen 11;
DE AltName: Full=Cancer/testis antigen 1.11;
DE Short=CT1.11;
DE AltName: Full=MAGE-11 antigen;
GN Name=MAGEA11 {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:6798};
GN Synonyms=MAGE11;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7927540; DOI=10.1007/bf01246677;
RA De Plaen E., Arden K., Traversari C., Gaforio J.J., Szikora J.-P.,
RA De Smet C., Brasseur F., van der Bruggen P., Lethe B.G., Lurquin C.,
RA Brasseur R., Chomez P., de Backer O., Cavenee W., Boon T.;
RT "Structure, chromosomal localization, and expression of 12 genes of the
RT MAGE family.";
RL Immunogenetics 40:360-369(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, AND
RP SUBCELLULAR LOCATION.
RC TISSUE=Testis;
RX PubMed=15684378; DOI=10.1128/mcb.25.4.1238-1257.2005;
RA Bai S., He B., Wilson E.M.;
RT "Melanoma antigen gene protein MAGE-11 regulates androgen receptor function
RT by modulating the interdomain interaction.";
RL Mol. Cell. Biol. 25:1238-1257(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Placenta;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP VARIANT PRO-57.
RX PubMed=28397838; DOI=10.1038/mp.2017.60;
RA Harripaul R., Vasli N., Mikhailov A., Rafiq M.A., Mittal K.,
RA Windpassinger C., Sheikh T.I., Noor A., Mahmood H., Downey S., Johnson M.,
RA Vleuten K., Bell L., Ilyas M., Khan F.S., Khan V., Moradi M., Ayaz M.,
RA Naeem F., Heidari A., Ahmed I., Ghadami S., Agha Z., Zeinali S., Qamar R.,
RA Mozhdehipanah H., John P., Mir A., Ansar M., French L., Ayub M.,
RA Vincent J.B.;
RT "Mapping autosomal recessive intellectual disability: combined microarray
RT and exome sequencing identifies 26 novel candidate genes in 192
RT consanguineous families.";
RL Mol. Psychiatry 23:973-984(2018).
CC -!- FUNCTION: Acts as androgen receptor coregulator that increases androgen
CC receptor activity by modulating the receptors interdomain interaction.
CC May play a role in embryonal development and tumor transformation or
CC aspects of tumor progression. {ECO:0000269|PubMed:15684378}.
CC -!- INTERACTION:
CC P43364; Q68CK6: ACSM2B; NbExp=3; IntAct=EBI-739552, EBI-2880280;
CC P43364; O95696: BRD1; NbExp=3; IntAct=EBI-739552, EBI-714754;
CC P43364; Q6P5X5: C22orf39; NbExp=3; IntAct=EBI-739552, EBI-7317823;
CC P43364; P55210: CASP7; NbExp=3; IntAct=EBI-739552, EBI-523958;
CC P43364; Q969G5: CAVIN3; NbExp=3; IntAct=EBI-739552, EBI-3893101;
CC P43364; Q8IYK2: CCDC105; NbExp=3; IntAct=EBI-739552, EBI-10818513;
CC P43364; Q9BWC9: CCDC106; NbExp=3; IntAct=EBI-739552, EBI-711501;
CC P43364; Q49A88-3: CCDC14; NbExp=3; IntAct=EBI-739552, EBI-12105646;
CC P43364; Q8IYE0: CCDC146; NbExp=3; IntAct=EBI-739552, EBI-10749669;
CC P43364; Q2M243: CCDC27; NbExp=3; IntAct=EBI-739552, EBI-12314269;
CC P43364; P42772: CDKN2B; NbExp=4; IntAct=EBI-739552, EBI-711280;
CC P43364; Q96AJ1: CLUAP1; NbExp=5; IntAct=EBI-739552, EBI-739780;
CC P43364; P31146: CORO1A; NbExp=3; IntAct=EBI-739552, EBI-1046676;
CC P43364; Q8WZ74: CTTNBP2; NbExp=3; IntAct=EBI-739552, EBI-1774260;
CC P43364; Q6IS01: DLGAP1; NbExp=3; IntAct=EBI-739552, EBI-11961832;
CC P43364; Q96BY6: DOCK10; NbExp=3; IntAct=EBI-739552, EBI-748520;
CC P43364; Q3B820: FAM161A; NbExp=3; IntAct=EBI-739552, EBI-719941;
CC P43364; Q8TAE8: GADD45GIP1; NbExp=3; IntAct=EBI-739552, EBI-372506;
CC P43364; P23434: GCSH; NbExp=3; IntAct=EBI-739552, EBI-715444;
CC P43364; P09067: HOXB5; NbExp=3; IntAct=EBI-739552, EBI-3893317;
CC P43364; Q8TCB0: IFI44; NbExp=3; IntAct=EBI-739552, EBI-2831730;
CC P43364; P20809: IL11; NbExp=4; IntAct=EBI-739552, EBI-751694;
CC P43364; P40189: IL6ST; NbExp=3; IntAct=EBI-739552, EBI-1030834;
CC P43364; Q92613: JADE3; NbExp=4; IntAct=EBI-739552, EBI-10278909;
CC P43364; Q8IYD9: LAS2; NbExp=4; IntAct=EBI-739552, EBI-749878;
CC P43364; A0A0S2Z5F8: LMBR1L; NbExp=3; IntAct=EBI-739552, EBI-16434477;
CC P43364; P58340: MLF1; NbExp=5; IntAct=EBI-739552, EBI-721328;
CC P43364; Q9Y6M9: NDUFB9; NbExp=4; IntAct=EBI-739552, EBI-713654;
CC P43364; O94818-2: NOL4; NbExp=3; IntAct=EBI-739552, EBI-10190763;
CC P43364; Q96HA8: NTAQ1; NbExp=3; IntAct=EBI-739552, EBI-741158;
CC P43364; Q9H0N5: PCBD2; NbExp=3; IntAct=EBI-739552, EBI-634289;
CC P43364; O14832: PHYH; NbExp=4; IntAct=EBI-739552, EBI-721853;
CC P43364; Q96FE7: PIK3IP1; NbExp=3; IntAct=EBI-739552, EBI-10285708;
CC P43364; Q9Y237-2: PIN4; NbExp=3; IntAct=EBI-739552, EBI-11749201;
CC P43364; Q63HM9: PLCXD3; NbExp=3; IntAct=EBI-739552, EBI-12105500;
CC P43364; P30405: PPIF; NbExp=3; IntAct=EBI-739552, EBI-5544229;
CC P43364; Q8N3J5: PPM1K; NbExp=3; IntAct=EBI-739552, EBI-3923368;
CC P43364; Q6VN20: RANBP10; NbExp=3; IntAct=EBI-739552, EBI-310569;
CC P43364; Q96EN9: REX1BD; NbExp=3; IntAct=EBI-739552, EBI-745810;
CC P43364; Q9H788: SH2D4A; NbExp=2; IntAct=EBI-739552, EBI-747035;
CC P43364; Q7Z614-3: SNX20; NbExp=3; IntAct=EBI-739552, EBI-12336127;
CC P43364; P49675: STAR; NbExp=6; IntAct=EBI-739552, EBI-722932;
CC P43364; Q9P2R7: SUCLA2; NbExp=3; IntAct=EBI-739552, EBI-2269898;
CC P43364; P51687: SUOX; NbExp=3; IntAct=EBI-739552, EBI-3921347;
CC P43364; Q15560: TCEA2; NbExp=5; IntAct=EBI-739552, EBI-710310;
CC P43364; Q9BQ70: TCF25; NbExp=5; IntAct=EBI-739552, EBI-745182;
CC P43364; Q8N131: TMEM123; NbExp=4; IntAct=EBI-739552, EBI-749248;
CC P43364; Q9NXH9: TRMT1; NbExp=5; IntAct=EBI-739552, EBI-748900;
CC P43364; Q7Z6J8: UBE3D; NbExp=3; IntAct=EBI-739552, EBI-9379147;
CC P43364; Q15007: WTAP; NbExp=4; IntAct=EBI-739552, EBI-751647;
CC P43364-2; Q8TDX5: ACMSD; NbExp=3; IntAct=EBI-10178634, EBI-749859;
CC P43364-2; I7GY12: B9838V1; NbExp=3; IntAct=EBI-10178634, EBI-10178638;
CC P43364-2; O43521: BCL2L11; NbExp=3; IntAct=EBI-10178634, EBI-526406;
CC P43364-2; Q9BXY8: BEX2; NbExp=3; IntAct=EBI-10178634, EBI-745073;
CC P43364-2; Q49A88: CCDC14; NbExp=3; IntAct=EBI-10178634, EBI-751035;
CC P43364-2; Q8IYE0-2: CCDC146; NbExp=3; IntAct=EBI-10178634, EBI-10247802;
CC P43364-2; Q86Y33: CDC20B; NbExp=3; IntAct=EBI-10178634, EBI-10260504;
CC P43364-2; Q96AJ1: CLUAP1; NbExp=3; IntAct=EBI-10178634, EBI-739780;
CC P43364-2; P68400: CSNK2A1; NbExp=3; IntAct=EBI-10178634, EBI-347804;
CC P43364-2; Q8IXB1-2: DNAJC10; NbExp=3; IntAct=EBI-10178634, EBI-10262451;
CC P43364-2; Q96BY6-3: DOCK10; NbExp=3; IntAct=EBI-10178634, EBI-10282566;
CC P43364-2; Q16206-2: ENOX2; NbExp=3; IntAct=EBI-10178634, EBI-10179508;
CC P43364-2; P46926: GNPDA1; NbExp=3; IntAct=EBI-10178634, EBI-749356;
CC P43364-2; P09067: HOXB5; NbExp=3; IntAct=EBI-10178634, EBI-3893317;
CC P43364-2; P20809: IL11; NbExp=3; IntAct=EBI-10178634, EBI-751694;
CC P43364-2; Q17RA0: IL6ST; NbExp=3; IntAct=EBI-10178634, EBI-10238517;
CC P43364-2; Q92613: JADE3; NbExp=3; IntAct=EBI-10178634, EBI-10278909;
CC P43364-2; Q13330: MTA1; NbExp=3; IntAct=EBI-10178634, EBI-714236;
CC P43364-2; Q9Y6M9: NDUFB9; NbExp=3; IntAct=EBI-10178634, EBI-713654;
CC P43364-2; P29474: NOS3; NbExp=3; IntAct=EBI-10178634, EBI-1391623;
CC P43364-2; Q96HA8: NTAQ1; NbExp=3; IntAct=EBI-10178634, EBI-741158;
CC P43364-2; Q9H0N5: PCBD2; NbExp=3; IntAct=EBI-10178634, EBI-634289;
CC P43364-2; Q9Y237: PIN4; NbExp=3; IntAct=EBI-10178634, EBI-714599;
CC P43364-2; Q8N490: PNKD; NbExp=3; IntAct=EBI-10178634, EBI-746368;
CC P43364-2; Q96JH8: RADIL; NbExp=3; IntAct=EBI-10178634, EBI-744267;
CC P43364-2; Q86U06: RBM23; NbExp=3; IntAct=EBI-10178634, EBI-780319;
CC P43364-2; Q86U06-2: RBM23; NbExp=3; IntAct=EBI-10178634, EBI-10258579;
CC P43364-2; Q7Z614: SNX20; NbExp=3; IntAct=EBI-10178634, EBI-744896;
CC P43364-2; P49675: STAR; NbExp=3; IntAct=EBI-10178634, EBI-722932;
CC P43364-2; Q9BQ70: TCF25; NbExp=3; IntAct=EBI-10178634, EBI-745182;
CC P43364-2; Q8N1Q8: THEM5; NbExp=3; IntAct=EBI-10178634, EBI-10264970;
CC P43364-2; Q8N131: TMEM123; NbExp=3; IntAct=EBI-10178634, EBI-749248;
CC P43364-2; Q5VU62: TPM3; NbExp=3; IntAct=EBI-10178634, EBI-10184033;
CC P43364-2; Q9NXH9: TRMT1; NbExp=3; IntAct=EBI-10178634, EBI-748900;
CC P43364-2; Q99757: TXN2; NbExp=3; IntAct=EBI-10178634, EBI-2932492;
CC P43364-2; Q9Y2K6: USP20; NbExp=3; IntAct=EBI-10178634, EBI-2511991;
CC P43364-2; Q68CQ4: UTP25; NbExp=3; IntAct=EBI-10178634, EBI-747711;
CC P43364-2; Q6PEW1: ZCCHC12; NbExp=3; IntAct=EBI-10178634, EBI-748373;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15684378}. Cytoplasm
CC {ECO:0000269|PubMed:15684378}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=P43364-1; Sequence=Displayed;
CC Name=2;
CC IsoId=P43364-2; Sequence=VSP_018576;
CC -!- TISSUE SPECIFICITY: Expressed in tumors of several types, such as
CC melanoma, head and neck squamous cell carcinoma, lung carcinoma and
CC breast carcinoma. Expressed in testis, ovary, prostate, cancerous
CC prostate, breast and adrenal tissue. {ECO:0000269|PubMed:15684378}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA68870.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; U10686; AAA68870.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AY747607; AAW71787.1; -; mRNA.
DR EMBL; AK127849; BAC87161.1; -; mRNA.
DR EMBL; BC004479; AAH04479.2; -; mRNA.
DR CCDS; CCDS48180.1; -. [P43364-1]
DR PIR; I38660; I38660.
DR RefSeq; NP_001011544.1; NM_001011544.1.
DR RefSeq; NP_005357.2; NM_005366.4. [P43364-1]
DR RefSeq; XP_016885010.1; XM_017029521.1.
DR RefSeq; XP_016885011.1; XM_017029522.1. [P43364-2]
DR PDB; 6WJH; X-ray; 2.19 A; A/B/C/D=218-429.
DR PDBsum; 6WJH; -.
DR AlphaFoldDB; P43364; -.
DR SMR; P43364; -.
DR BioGRID; 110284; 146.
DR IntAct; P43364; 115.
DR MINT; P43364; -.
DR STRING; 9606.ENSP00000347358; -.
DR MoonDB; P43364; Predicted.
DR iPTMnet; P43364; -.
DR PhosphoSitePlus; P43364; -.
DR BioMuta; MAGEA11; -.
DR DMDM; 97536722; -.
DR MassIVE; P43364; -.
DR MaxQB; P43364; -.
DR PaxDb; P43364; -.
DR PeptideAtlas; P43364; -.
DR PRIDE; P43364; -.
DR ProteomicsDB; 55626; -. [P43364-1]
DR ProteomicsDB; 55627; -. [P43364-2]
DR TopDownProteomics; P43364-1; -. [P43364-1]
DR Antibodypedia; 30628; 234 antibodies from 30 providers.
DR DNASU; 4110; -.
DR Ensembl; ENST00000355220.6; ENSP00000347358.5; ENSG00000185247.15. [P43364-1]
DR GeneID; 4110; -.
DR KEGG; hsa:4110; -.
DR MANE-Select; ENST00000355220.6; ENSP00000347358.5; NM_005366.5; NP_005357.2.
DR UCSC; uc004fdq.4; human. [P43364-1]
DR CTD; 4110; -.
DR DisGeNET; 4110; -.
DR GeneCards; MAGEA11; -.
DR HGNC; HGNC:6798; MAGEA11.
DR HPA; ENSG00000185247; Tissue enriched (epididymis).
DR MIM; 300344; gene.
DR neXtProt; NX_P43364; -.
DR OpenTargets; ENSG00000185247; -.
DR PharmGKB; PA30544; -.
DR VEuPathDB; HostDB:ENSG00000185247; -.
DR eggNOG; KOG4562; Eukaryota.
DR GeneTree; ENSGT00940000164167; -.
DR InParanoid; P43364; -.
DR OMA; KNYEEYF; -.
DR OrthoDB; 1195799at2759; -.
DR PhylomeDB; P43364; -.
DR TreeFam; TF328505; -.
DR PathwayCommons; P43364; -.
DR SignaLink; P43364; -.
DR SIGNOR; P43364; -.
DR BioGRID-ORCS; 4110; 12 hits in 693 CRISPR screens.
DR GeneWiki; MAGEA11; -.
DR GenomeRNAi; 4110; -.
DR Pharos; P43364; Tbio.
DR PRO; PR:P43364; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; P43364; protein.
DR Bgee; ENSG00000185247; Expressed in corpus epididymis and 28 other tissues.
DR ExpressionAtlas; P43364; baseline and differential.
DR Genevisible; P43364; HS.
DR GO; GO:0005829; C:cytosol; IDA:HPA.
DR GO; GO:0016604; C:nuclear body; IDA:HPA.
DR GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0042826; F:histone deacetylase binding; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.1200; -; 1.
DR Gene3D; 1.10.10.1210; -; 1.
DR InterPro; IPR037445; MAGE.
DR InterPro; IPR021072; MAGE_N.
DR InterPro; IPR041898; MAGE_WH1.
DR InterPro; IPR041899; MAGE_WH2.
DR InterPro; IPR030099; MAGEA11.
DR InterPro; IPR002190; MHD_dom.
DR PANTHER; PTHR11736; PTHR11736; 1.
DR PANTHER; PTHR11736:SF146; PTHR11736:SF146; 1.
DR Pfam; PF01454; MAGE; 1.
DR Pfam; PF12440; MAGE_N; 1.
DR SMART; SM01373; MAGE; 1.
DR SMART; SM01392; MAGE_N; 1.
DR PROSITE; PS50838; MAGE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Cytoplasm; Nucleus; Reference proteome;
KW Tumor antigen.
FT CHAIN 1..429
FT /note="Melanoma-associated antigen 11"
FT /id="PRO_0000156710"
FT DOMAIN 222..421
FT /note="MAGE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00127"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..35
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_018576"
FT VARIANT 57
FT /note="S -> P (found in a family with intellectual
FT disability; unknown pathological significance;
FT dbSNP:rs1557362265)"
FT /evidence="ECO:0000269|PubMed:28397838"
FT /id="VAR_080775"
FT VARIANT 191
FT /note="S -> R (in dbSNP:rs2233049)"
FT /id="VAR_053497"
FT HELIX 221..238
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 245..251
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 254..259
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 260..275
FT /evidence="ECO:0007829|PDB:6WJH"
FT STRAND 277..283
FT /evidence="ECO:0007829|PDB:6WJH"
FT TURN 284..287
FT /evidence="ECO:0007829|PDB:6WJH"
FT STRAND 288..293
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 294..296
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 312..324
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 331..338
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 339..341
FT /evidence="ECO:0007829|PDB:6WJH"
FT TURN 350..352
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 355..360
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 362..365
FT /evidence="ECO:0007829|PDB:6WJH"
FT STRAND 368..373
FT /evidence="ECO:0007829|PDB:6WJH"
FT STRAND 382..386
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 388..393
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 396..406
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 411..413
FT /evidence="ECO:0007829|PDB:6WJH"
FT HELIX 415..422
FT /evidence="ECO:0007829|PDB:6WJH"
SQ SEQUENCE 429 AA; 48129 MW; FB399ABF47B4C49B CRC64;
METQFRRGGL GCSPASIKRK KKREDSGDFG LQVSTMFSED DFQSTERAPY GPQLQWSQDL
PRVQVFREQA NLEDRSPRRT QRITGGEQVL WGPITQIFPT VRPADLTRVI MPLEQRSQHC
KPEEGLQAQE EDLGLVGAQA LQAEEQEAAF FSSTLNVGTL EELPAAESPS PPQSPQEESF
SPTAMDAIFG SLSDEGSGSQ EKEGPSTSPD LIDPESFSQD ILHDKIIDLV HLLLRKYRVK
GLITKAEMLG SVIKNYEDYF PEIFREASVC MQLLFGIDVK EVDPTSHSYV LVTSLNLSYD
GIQCNEQSMP KSGLLIIVLG VIFMEGNCIP EEVMWEVLSI MGVYAGREHF LFGEPKRLLT
QNWVQEKYLV YRQVPGTDPA CYEFLWGPRA HAETSKMKVL EYIANANGRD PTSYPSLYED
ALREEGEGV
