ID   MAGH1_MOUSE             Reviewed;         218 AA.
AC   Q9NWG9; Q99PB0;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Melanoma-associated antigen H1;
DE   AltName: Full=MAGE-H1 antigen;
GN   Name=Mageh1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Auquier P.H., Chomez P.M., De Backer O.R., Bertrand M.J.M.;
RT   "Ten new murine members of the MAGE gene family.";
RL   Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Isogai T., Ota T., Hayashi K., Sugiyama T., Otsuki T., Suzuki Y.,
RA   Nishikawa T., Nagai K., Sugano S., Takahashi-Fujii A., Hara H., Tanase T.,
RA   Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M.,
RA   Nabekura T., Ishii S., Kawai Y., Saito K., Yamamoto J., Wakamatsu A.,
RA   Nakamura Y., Nagahari K., Masuho Y., Oshima A.;
RT   "NEDO cDNA sequencing project.";
RL   Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AF319981; AAK01209.1; -; mRNA.
DR   EMBL; AK000896; BAA91412.1; -; mRNA.
DR   EMBL; BC051935; AAH51935.1; -; mRNA.
DR   CCDS; CCDS30478.1; -.
DR   RefSeq; NP_076277.1; NM_023788.3.
DR   AlphaFoldDB; Q9NWG9; -.
DR   SMR; Q9NWG9; -.
DR   STRING; 10090.ENSMUSP00000057157; -.
DR   iPTMnet; Q9NWG9; -.
DR   PhosphoSitePlus; Q9NWG9; -.
DR   MaxQB; Q9NWG9; -.
DR   PaxDb; Q9NWG9; -.
DR   PRIDE; Q9NWG9; -.
DR   ProteomicsDB; 287298; -.
DR   Antibodypedia; 568; 154 antibodies from 28 providers.
DR   DNASU; 75625; -.
DR   Ensembl; ENSMUST00000051484; ENSMUSP00000057157; ENSMUSG00000047238.
DR   GeneID; 75625; -.
DR   KEGG; mmu:75625; -.
DR   UCSC; uc009uqq.1; mouse.
DR   CTD; 28986; -.
DR   MGI; MGI:1922875; Mageh1.
DR   VEuPathDB; HostDB:ENSMUSG00000047238; -.
DR   eggNOG; KOG4562; Eukaryota.
DR   GeneTree; ENSGT00840000130063; -.
DR   HOGENOM; CLU_107642_0_0_1; -.
DR   InParanoid; Q9NWG9; -.
DR   OMA; YDWDSED; -.
DR   OrthoDB; 1195799at2759; -.
DR   PhylomeDB; Q9NWG9; -.
DR   TreeFam; TF328505; -.
DR   BioGRID-ORCS; 75625; 2 hits in 73 CRISPR screens.
DR   PRO; PR:Q9NWG9; -.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; Q9NWG9; protein.
DR   Bgee; ENSMUSG00000047238; Expressed in median eminence of neurohypophysis and 275 other tissues.
DR   ExpressionAtlas; Q9NWG9; baseline and differential.
DR   Genevisible; Q9NWG9; MM.
DR   GO; GO:0005737; C:cytoplasm; ISO:MGI.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.1210; -; 1.
DR   InterPro; IPR037445; MAGE.
DR   InterPro; IPR041899; MAGE_WH2.
DR   InterPro; IPR002190; MHD_dom.
DR   PANTHER; PTHR11736; PTHR11736; 1.
DR   Pfam; PF01454; MAGE; 1.
DR   SMART; SM01373; MAGE; 1.
DR   PROSITE; PS50838; MAGE; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome; Tumor antigen.
FT   CHAIN           1..218
FT                   /note="Melanoma-associated antigen H1"
FT                   /id="PRO_0000156736"
FT   DOMAIN          1..197
FT                   /note="MAGE"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00127"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         194
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5PPP4"
SQ   SEQUENCE   218 AA;  24325 MW;  D21F5F319CB93508 CRC64;
     MPRGRKSRRR RNAKAAEENR NNRKSQASEA SETPMAASVA PSTPEEYLSG PEEDTSTLEK
     ASSTPSEASS TALVQKPVTR SNFQGTKKSL LMSILALIFI MGNSAKEALV WKVLGKLGMQ
     PGRQHSIFGD PKKVVTEEFV RRGYLIYKPV PRSSPVEYEF FWGPRAHVES SKLKVMHFVA
     RVRNRCSKDW PCNYDWDSDD DAEVEAILNS GARGYSAP