MAGH1_RAT
ID MAGH1_RAT Reviewed; 218 AA.
AC Q5PPP4;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Melanoma-associated antigen H1;
DE AltName: Full=MAGE-H1 antigen;
GN Name=Mageh1;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-194, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=16641100; DOI=10.1073/pnas.0600895103;
RA Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A.;
RT "Quantitative phosphoproteomics of vasopressin-sensitive renal cells:
RT regulation of aquaporin-2 phosphorylation at two sites.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006).
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DR EMBL; BC087574; AAH87574.1; -; mRNA.
DR RefSeq; NP_001013268.1; NM_001013250.1.
DR AlphaFoldDB; Q5PPP4; -.
DR SMR; Q5PPP4; -.
DR STRING; 10116.ENSRNOP00000004238; -.
DR iPTMnet; Q5PPP4; -.
DR PhosphoSitePlus; Q5PPP4; -.
DR PaxDb; Q5PPP4; -.
DR GeneID; 367767; -.
DR KEGG; rno:367767; -.
DR UCSC; RGD:1359316; rat.
DR CTD; 28986; -.
DR RGD; 1359316; Mageh1.
DR VEuPathDB; HostDB:ENSRNOG00000003178; -.
DR eggNOG; KOG4562; Eukaryota.
DR HOGENOM; CLU_107642_0_0_1; -.
DR InParanoid; Q5PPP4; -.
DR OMA; YDWDSED; -.
DR OrthoDB; 1195799at2759; -.
DR PhylomeDB; Q5PPP4; -.
DR TreeFam; TF328505; -.
DR PRO; PR:Q5PPP4; -.
DR Proteomes; UP000002494; Chromosome X.
DR Bgee; ENSRNOG00000003178; Expressed in pancreas and 19 other tissues.
DR Genevisible; Q5PPP4; RN.
DR GO; GO:0005737; C:cytoplasm; IDA:RGD.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; NAS:RGD.
DR Gene3D; 1.10.10.1210; -; 1.
DR InterPro; IPR037445; MAGE.
DR InterPro; IPR041899; MAGE_WH2.
DR InterPro; IPR002190; MHD_dom.
DR PANTHER; PTHR11736; PTHR11736; 1.
DR Pfam; PF01454; MAGE; 1.
DR SMART; SM01373; MAGE; 1.
DR PROSITE; PS50838; MAGE; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Tumor antigen.
FT CHAIN 1..218
FT /note="Melanoma-associated antigen H1"
FT /id="PRO_0000156737"
FT DOMAIN 1..197
FT /note="MAGE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00127"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 194
FT /note="Phosphotyrosine"
FT /evidence="ECO:0007744|PubMed:16641100"
SQ SEQUENCE 218 AA; 24289 MW; A9756275DC49B3A5 CRC64;
MPRGRKSRRR RNAKAAEENR NNRKIQASEA SKTPMAASVT PSTPEEYLSG PEEDTSTPEK
ASSTLAEASS TALVQKPVTR SNFQGTKKSL LMSILALIFI MGNSAKEALV WKVLGKLGMQ
PGRQHSIFGD PKKVVTEEFV RRGYLIYKPV PRSSPVEYEF FWGPRAHVES SKLKVMHFVA
RVRNRCSKDW PCNYDWDSDD DAEVEAILNS GARGSSAP
