ID   MAJE_PSEAE              Reviewed;         172 AA.
AC   Q9HI36;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Major exported protein;
DE   AltName: Full=Secreted protein hcp;
GN   Name=hcpA; OrderedLocusNames=PA0263;
GN   and
GN   Name=hcpB; OrderedLocusNames=PA1512;
GN   and
GN   Name=hcpC; OrderedLocusNames=PA5267;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the hcp1 family. {ECO:0000305}.
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DR   EMBL; AE004091; AAG03652.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG04901.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG08652.1; -; Genomic_DNA.
DR   PIR; G82987; G82987.
DR   RefSeq; NP_248954.1; NC_002516.2.
DR   RefSeq; NP_250203.1; NC_002516.2.
DR   RefSeq; NP_253954.1; NC_002516.2.
DR   RefSeq; WP_003083317.1; NZ_CP053028.1.
DR   PDB; 3HE1; X-ray; 2.10 A; A/B/C/D/E/F=1-172.
DR   PDBsum; 3HE1; -.
DR   AlphaFoldDB; Q9HI36; -.
DR   SMR; Q9HI36; -.
DR   STRING; 287.DR97_2638; -.
DR   PaxDb; Q9HI36; -.
DR   PRIDE; Q9HI36; -.
DR   DNASU; 879579; -.
DR   EnsemblBacteria; AAG03652; AAG03652; PA0263.
DR   EnsemblBacteria; AAG04901; AAG04901; PA1512.
DR   EnsemblBacteria; AAG08652; AAG08652; PA5267.
DR   GeneID; 879579; -.
DR   GeneID; 880866; -.
DR   GeneID; 883081; -.
DR   KEGG; pae:PA0263; -.
DR   KEGG; pae:PA1512; -.
DR   KEGG; pae:PA5267; -.
DR   PATRIC; fig|208964.12.peg.1564; -.
DR   PseudoCAP; PA0263; -.
DR   PseudoCAP; PA1512; -.
DR   PseudoCAP; PA5267; -.
DR   HOGENOM; CLU_116190_1_0_6; -.
DR   InParanoid; Q9HI36; -.
DR   OMA; WEHTTAG; -.
DR   PhylomeDB; Q9HI36; -.
DR   EvolutionaryTrace; Q9HI36; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.110.20; -; 1.
DR   InterPro; IPR036624; Hcp1-lik_sf.
DR   InterPro; IPR008514; T6SS_Hcp.
DR   Pfam; PF05638; T6SS_HCP; 1.
DR   SUPFAM; SSF141452; SSF141452; 1.
DR   TIGRFAMs; TIGR03344; VI_effect_Hcp1; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Secreted.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..172
FT                   /note="Major exported protein"
FT                   /id="PRO_0000288024"
FT   STRAND          5..11
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   TURN            12..14
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   TURN            17..20
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   HELIX           24..27
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   HELIX           28..30
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          38..41
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          43..45
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          68..74
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   HELIX           78..87
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          90..101
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          105..127
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          140..147
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          149..155
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   TURN            156..158
FT                   /evidence="ECO:0007829|PDB:3HE1"
FT   STRAND          161..165
FT                   /evidence="ECO:0007829|PDB:3HE1"
SQ   SEQUENCE   172 AA;  19091 MW;  8565ABE2F64B9577 CRC64;
     MATPAYMSIT GTKQGLITAG AFTEDSVGNT YQEGHEDQVM VQGFNHEVII PRDPQSGQPT
     GQRVHKPVVI TKVFDKASPL LLAALTSGER LTKVEIQWYR TSAAGTQEHY YTTVLEDAII
     VDIKDYMHNC QDPGNAHFTH LEDVHFTYRK ITWTHEVSGT SGSDDWRSPV AG