ID   MAK16_BOVIN             Reviewed;         298 AA.
AC   Q1RML7;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Protein MAK16 homolog;
GN   Name=MAK16;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAK16 family. {ECO:0000305}.
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DR   EMBL; BC114829; AAI14830.1; -; mRNA.
DR   RefSeq; NP_001068638.1; NM_001075170.1.
DR   AlphaFoldDB; Q1RML7; -.
DR   SMR; Q1RML7; -.
DR   STRING; 9913.ENSBTAP00000044825; -.
DR   PaxDb; Q1RML7; -.
DR   PRIDE; Q1RML7; -.
DR   Ensembl; ENSBTAT00000047639; ENSBTAP00000044825; ENSBTAG00000033504.
DR   GeneID; 504683; -.
DR   KEGG; bta:504683; -.
DR   CTD; 84549; -.
DR   VEuPathDB; HostDB:ENSBTAG00000033504; -.
DR   VGNC; VGNC:31153; MAK16.
DR   eggNOG; KOG3064; Eukaryota.
DR   GeneTree; ENSGT00390000012859; -.
DR   HOGENOM; CLU_050888_2_0_1; -.
DR   InParanoid; Q1RML7; -.
DR   OMA; GTYRDIY; -.
DR   OrthoDB; 1394336at2759; -.
DR   TreeFam; TF105759; -.
DR   Proteomes; UP000009136; Chromosome 27.
DR   Bgee; ENSBTAG00000033504; Expressed in conceptus and 105 other tissues.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   InterPro; IPR029004; L28e/Mak16.
DR   InterPro; IPR006958; Mak16.
DR   Pfam; PF04874; Mak16; 1.
DR   Pfam; PF01778; Ribosomal_L28e; 1.
DR   PIRSF; PIRSF003352; MAK16; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome;
KW   Ubl conjugation.
FT   CHAIN           1..298
FT                   /note="Protein MAK16 homolog"
FT                   /id="PRO_0000343653"
FT   REGION          190..276
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..252
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..268
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   MOD_RES         197
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   MOD_RES         200
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   MOD_RES         228
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   MOD_RES         231
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   CROSSLNK        55
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
FT   CROSSLNK        151
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXY0"
SQ   SEQUENCE   298 AA;  35289 MW;  751EA3D46BD31B58 CRC64;
     MQSDDVIWDT LGNKQFCSFK IRTKTQSFCR NEYSLTGLCN RSSCPLANSQ YATIKEEKGQ
     CYLYMKVIER AAFPRRLWER VRLHKNYEKA LEQIDENLIY WPRFIRHKCK QRFTKITQYL
     IRIRKLTLKR QRKLVPLSKK VERREKRREE KALIAAQLDN AIEKELLERL KQDTYGDIYN
     FPIHAFDKAL EQQEAESDSS DAEEKDDEED EEDVGKREFV EDDEVDESDI SDFEDMDKLD
     ASSDEDQDDK SSSEEEEKTL DAKHKGKTPL KGPLRRKRAY VEIEYEQETE PAAKAKTT