ID   MAK16_DICDI             Reviewed;         309 AA.
AC   Q55DJ3;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Protein MAK16 homolog;
DE   AltName: Full=MAK16-like protein;
GN   Name=mak16l; Synonyms=mak16; ORFNames=DDB_G0269642;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAK16 family. {ECO:0000305}.
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DR   EMBL; AAFI02000005; EAL72171.1; -; Genomic_DNA.
DR   RefSeq; XP_646138.1; XM_641046.1.
DR   AlphaFoldDB; Q55DJ3; -.
DR   SMR; Q55DJ3; -.
DR   STRING; 44689.DDB0235209; -.
DR   PaxDb; Q55DJ3; -.
DR   EnsemblProtists; EAL72171; EAL72171; DDB_G0269642.
DR   GeneID; 8617088; -.
DR   KEGG; ddi:DDB_G0269642; -.
DR   dictyBase; DDB_G0269642; mak16l.
DR   eggNOG; KOG3064; Eukaryota.
DR   HOGENOM; CLU_050888_0_1_1; -.
DR   InParanoid; Q55DJ3; -.
DR   OMA; GTYRDIY; -.
DR   PhylomeDB; Q55DJ3; -.
DR   PRO; PR:Q55DJ3; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005730; C:nucleolus; ISS:dictyBase.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; ISS:dictyBase.
DR   InterPro; IPR029004; L28e/Mak16.
DR   InterPro; IPR006958; Mak16.
DR   Pfam; PF04874; Mak16; 1.
DR   Pfam; PF01778; Ribosomal_L28e; 1.
DR   PIRSF; PIRSF003352; MAK16; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..309
FT                   /note="Protein MAK16 homolog"
FT                   /id="PRO_0000328353"
FT   REGION          194..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..270
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   309 AA;  36620 MW;  63E380A913D25F48 CRC64;
     MQSDDIIWDV INKNFCSFKT TFNKTKFCKN EYNVTGVCNK VSCPLANSRY ATVREEEGVC
     YLYMKTVERA HTPNRLWEKI KLDPNFMKAI EQIDSHLEFW PGHMSHRVKQ RYIRITQYLI
     RMRKMRKQIK RELVPIKKKA ERRDATRENK ALIAAHLTTN IKKELLERLN KGTYADMHYF
     PEDIINNVLE KEGEADQFSE EEADENEEEG EEEMEEEFED DIDDIEDAGG AFEYVEGDDD
     EDDIDDEYEN EPYQDDDEED DDDDDDDDEE VKPQITKKRG PTFKPTKKTP QKRVHMEVEI
     EEETENQAN