ID   MAK16_SCHPO             Reviewed;         302 AA.
AC   Q9UTE6;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Protein mak16;
GN   Name=mak16; ORFNames=SPAC222.06;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the MAK16 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB60698.1; -; Genomic_DNA.
DR   PIR; T50147; T50147.
DR   RefSeq; NP_593145.1; NM_001018542.2.
DR   AlphaFoldDB; Q9UTE6; -.
DR   SMR; Q9UTE6; -.
DR   BioGRID; 278431; 7.
DR   STRING; 4896.SPAC222.06.1; -.
DR   iPTMnet; Q9UTE6; -.
DR   MaxQB; Q9UTE6; -.
DR   PaxDb; Q9UTE6; -.
DR   EnsemblFungi; SPAC222.06.1; SPAC222.06.1:pep; SPAC222.06.
DR   GeneID; 2541944; -.
DR   KEGG; spo:SPAC222.06; -.
DR   PomBase; SPAC222.06; mak16.
DR   VEuPathDB; FungiDB:SPAC222.06; -.
DR   eggNOG; KOG3064; Eukaryota.
DR   HOGENOM; CLU_050888_0_1_1; -.
DR   InParanoid; Q9UTE6; -.
DR   OMA; GTYRDIY; -.
DR   PhylomeDB; Q9UTE6; -.
DR   PRO; PR:Q9UTE6; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005730; C:nucleolus; ISS:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   InterPro; IPR029004; L28e/Mak16.
DR   InterPro; IPR006958; Mak16.
DR   Pfam; PF04874; Mak16; 1.
DR   Pfam; PF01778; Ribosomal_L28e; 1.
DR   PIRSF; PIRSF003352; MAK16; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..302
FT                   /note="Protein mak16"
FT                   /id="PRO_0000339417"
FT   REGION          198..302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           138..143
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           274..282
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        198..228
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        237..256
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..302
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   302 AA;  35627 MW;  5C08899FF29C0E67 CRC64;
     MQQDEVIWQV VGHEFCSYRI KGEAQNFCRN EYNVTGLCNR QSCPLANSRY ATVREDNGKL
     YLYMKTIERA HFPSKLWQRI KLSKNYAKAL EQIDQQLLYW PGRQIHRCKQ RLTRLTQYLL
     KARRLALKHQ PALIPIKPKQ AHREASRERK ALIAAKLEKN IEKELVKRLK SGVYGDQPLN
     VNEEIWNKVL AAREGLIDEG EEEEEREEAE LEFVSDDEDE EEISDLEDWL GSDQSMETSE
     SEEEESSESE SDEDEDEDNK GKIRKRKTDD AKKSRKKRAP HIHIEYEQER ENEKIPAVQH
     SW