MAK32_YEAST
ID MAK32_YEAST Reviewed; 363 AA.
AC P23060; D6VR27;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Protein MAK32;
DE AltName: Full=Maintenance of killer protein 32;
GN Name=MAK32; OrderedLocusNames=YCR019W; ORFNames=YCR19W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3916862; DOI=10.1002/yea.320010204;
RA Toh-e A., Sahashi Y.;
RT "The PET18 locus of Saccharomyces cerevisiae: a complex locus containing
RT multiple genes.";
RL Yeast 1:159-171(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=1574125; DOI=10.1038/357038a0;
RA Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA Sgouros J.G.;
RT "The complete DNA sequence of yeast chromosome III.";
RL Nature 357:38-46(1992).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
CC -!- FUNCTION: Necessary for the structural stability of L-A double-stranded
CC RNA-containing particles. Necessary for growth at 37 degrees Celsius as
CC well as for maintenance of the killer plasmid.
CC -!- SIMILARITY: To S.pombe SpAC4G8.14c. {ECO:0000305}.
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DR EMBL; X59720; CAA42310.1; -; Genomic_DNA.
DR EMBL; AY693011; AAT93030.1; -; Genomic_DNA.
DR EMBL; BK006937; DAA07496.1; -; Genomic_DNA.
DR PIR; S19429; BVBYK2.
DR RefSeq; NP_009946.1; NM_001178732.1.
DR AlphaFoldDB; P23060; -.
DR SMR; P23060; -.
DR BioGRID; 31000; 34.
DR IntAct; P23060; 1.
DR STRING; 4932.YCR019W; -.
DR MaxQB; P23060; -.
DR PaxDb; P23060; -.
DR PRIDE; P23060; -.
DR EnsemblFungi; YCR019W_mRNA; YCR019W; YCR019W.
DR GeneID; 850381; -.
DR KEGG; sce:YCR019W; -.
DR SGD; S000000612; MAK32.
DR VEuPathDB; FungiDB:YCR019W; -.
DR eggNOG; ENOG502RXN8; Eukaryota.
DR HOGENOM; CLU_032834_0_0_1; -.
DR InParanoid; P23060; -.
DR OMA; RGWNGYV; -.
DR BioCyc; YEAST:G3O-29334-MON; -.
DR PRO; PR:P23060; -.
DR Proteomes; UP000002311; Chromosome III.
DR RNAct; P23060; protein.
DR CDD; cd01943; MAK32; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR034094; Mak32.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR Pfam; PF00294; PfkB; 1.
DR SUPFAM; SSF53613; SSF53613; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..363
FT /note="Protein MAK32"
FT /id="PRO_0000084555"
FT CONFLICT 15
FT /note="I -> II (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 82
FT /note="Missing (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 363 AA; 40783 MW; CFB358F8ACF6EA4C CRC64;
MMNEEDSTET KSLVITNGMF IIDDIERSKY NIHYKNVPGG GGTFAILGAC IISSGNVTSK
GLKWIVDRGS DFPKEVIREI DSWGTDVRFR DDFSRLTTKG LNYYEGSDDL RKFKFLTPKK
QINVDDWIST FGQKIIDEMH AFHLLCSGSR CLDIINDLLR VKSSKGTKPI VIWEPFPDLC
DFDHQNDIKS VMQRNDVTVI LSPNAEESSR LFGLSSKEPT SLEECLALAH RFDDFMDENN
MCILRCGALG SISVSEKFKN GRTYDHFPAY HFKTQSKVLD PTGGGNSFLG GFAVSYALTK
SLDIASICGN IAAGAIIEQF GIPRYDPIAK TWNGITFLDR LKFYLSQSGL QYNINDLYKS
LTR
