ID   MAKR3_ARATH             Reviewed;         321 AA.
AC   Q9ZUS8; Q0WVJ4;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Probable membrane-associated kinase regulator 3;
GN   Name=MAKR3; OrderedLocusNames=At2g37380; ORFNames=F3G5.17;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Cheuk R., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA   Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA   Shinozaki K., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=21289069; DOI=10.1101/gad.2001911;
RA   Jaillais Y., Hothorn M., Belkhadir Y., Dabi T., Nimchuk Z.L.,
RA   Meyerowitz E.M., Chory J.;
RT   "Tyrosine phosphorylation controls brassinosteroid receptor activation by
RT   triggering membrane release of its kinase inhibitor.";
RL   Genes Dev. 25:232-237(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC005896; AAC98057.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC09390.1; -; Genomic_DNA.
DR   EMBL; BT011736; AAS49099.1; -; mRNA.
DR   EMBL; AK226754; BAE98854.1; -; mRNA.
DR   PIR; A84792; A84792.
DR   RefSeq; NP_181274.1; NM_129293.4.
DR   AlphaFoldDB; Q9ZUS8; -.
DR   STRING; 3702.AT2G37380.1; -.
DR   PaxDb; Q9ZUS8; -.
DR   PRIDE; Q9ZUS8; -.
DR   ProteomicsDB; 238512; -.
DR   EnsemblPlants; AT2G37380.1; AT2G37380.1; AT2G37380.
DR   GeneID; 818314; -.
DR   Gramene; AT2G37380.1; AT2G37380.1; AT2G37380.
DR   KEGG; ath:AT2G37380; -.
DR   Araport; AT2G37380; -.
DR   TAIR; locus:2049832; AT2G37380.
DR   eggNOG; ENOG502RCYF; Eukaryota.
DR   HOGENOM; CLU_048960_0_0_1; -.
DR   InParanoid; Q9ZUS8; -.
DR   OMA; HCATKAS; -.
DR   OrthoDB; 1117885at2759; -.
DR   PhylomeDB; Q9ZUS8; -.
DR   PRO; PR:Q9ZUS8; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9ZUS8; baseline and differential.
DR   Genevisible; Q9ZUS8; AT.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019210; F:kinase inhibitor activity; IEA:InterPro.
DR   InterPro; IPR039620; BKI1/MAKR1/3/4.
DR   PANTHER; PTHR33312; PTHR33312; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome.
FT   CHAIN           1..321
FT                   /note="Probable membrane-associated kinase regulator 3"
FT                   /id="PRO_0000410478"
FT   REGION          297..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        109
FT                   /note="A -> V (in Ref. 4; BAE98854)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   321 AA;  34974 MW;  7E76DD64A49CBAEB CRC64;
     MDLHESESRT HVLSTDGDDG YIDMEVNLSS SSSSSTSSSS FFSFPVTSSP PQSREFEFQM
     CSSAVASGES TTSPADELFY KGQLLPLHLP PRLKMVQKLL LASSSSTAAT ETPISPRAAA
     DVLSPRRFSS CEIGQDENCF FEISTELKRF IESNENHLGN SWSKKIKHSS ITQKLKASRA
     YIKALFSKQA CSDSSEINPR FKIEPSKVSR KKNPFVNSEN PLLIHRRSFS GVIQRHSQAK
     CSTSSSSSSS ASSLSSSFSF GSNGSLDLQT LMRSSNASDN SIEGAIEHCK QSFTTRKSNV
     TESELCSSRT SVSTCGDLDK D