MAKR6_ARATH
ID MAKR6_ARATH Reviewed; 235 AA.
AC Q84JK8; Q8LEK7; Q9FLX1;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Probable membrane-associated kinase regulator 6;
GN Name=MAKR6; OrderedLocusNames=At5g52900; ORFNames=MXC20.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION.
RX PubMed=15772289; DOI=10.1105/tpc.104.027474;
RA Osakabe Y., Maruyama K., Seki M., Satou M., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "Leucine-rich repeat receptor-like kinase1 is a key membrane-bound
RT regulator of abscisic acid early signaling in Arabidopsis.";
RL Plant Cell 17:1105-1119(2005).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21289069; DOI=10.1101/gad.2001911;
RA Jaillais Y., Hothorn M., Belkhadir Y., Dabi T., Nimchuk Z.L.,
RA Meyerowitz E.M., Chory J.;
RT "Tyrosine phosphorylation controls brassinosteroid receptor activation by
RT triggering membrane release of its kinase inhibitor.";
RL Genes Dev. 25:232-237(2011).
CC -!- FUNCTION: May be involved in abscisic acid signaling by acting as a
CC kinase regulator. {ECO:0000269|PubMed:15772289}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10438.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB009055; BAB10438.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96275.1; -; Genomic_DNA.
DR EMBL; BT005766; AAO64170.1; -; mRNA.
DR EMBL; BT006089; AAP04074.1; -; mRNA.
DR EMBL; AY085371; AAM62601.1; -; mRNA.
DR EMBL; AK228555; BAF00476.1; -; mRNA.
DR RefSeq; NP_568780.1; NM_124668.3.
DR AlphaFoldDB; Q84JK8; -.
DR STRING; 3702.AT5G52900.1; -.
DR iPTMnet; Q84JK8; -.
DR PaxDb; Q84JK8; -.
DR PRIDE; Q84JK8; -.
DR ProteomicsDB; 238762; -.
DR EnsemblPlants; AT5G52900.1; AT5G52900.1; AT5G52900.
DR GeneID; 835367; -.
DR Gramene; AT5G52900.1; AT5G52900.1; AT5G52900.
DR KEGG; ath:AT5G52900; -.
DR Araport; AT5G52900; -.
DR TAIR; locus:2176892; AT5G52900.
DR eggNOG; ENOG502QPRB; Eukaryota.
DR HOGENOM; CLU_082878_0_0_1; -.
DR InParanoid; Q84JK8; -.
DR OMA; DEYRKSC; -.
DR OrthoDB; 1144555at2759; -.
DR PhylomeDB; Q84JK8; -.
DR PRO; PR:Q84JK8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q84JK8; baseline and differential.
DR Genevisible; Q84JK8; AT.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR044699; MAKR6.
DR PANTHER; PTHR34576; PTHR34576; 1.
PE 2: Evidence at transcript level;
KW Abscisic acid signaling pathway; Cell membrane; Membrane;
KW Reference proteome.
FT CHAIN 1..235
FT /note="Probable membrane-associated kinase regulator 6"
FT /id="PRO_0000410481"
FT REGION 108..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 4
FT /note="G -> D (in Ref. 4; AAM62601)"
FT /evidence="ECO:0000305"
FT CONFLICT 40
FT /note="Y -> F (in Ref. 4; AAM62601)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 235 AA; 27070 MW; 99C8229A0B7A9105 CRC64;
MEEGKQEASM PLVPIDSFSY SWLVNFPSLE ATIDDHHQTY EDSSSSSSFI EMDPRLPPSR
RFFIKTSHES SFKFDNFVSF SDEDHSLVHA DELFRDGYVM PYRLKPTSAA TEEESEPLDT
TTSEKIDTRG LNSKPSPTSS RKLRRVSKWV LLKYLDFLTP LCKRLRRCRS AVTTGSIGMD
SRIRVTTSCR SRVYSDEMTS SPRISVADDY YWRRSCDSES SIYEAVLHCK KSFEK
