ID   MALA_STRP1              Reviewed;         271 AA.
AC   Q99ZB6; Q48Y92;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Maltodextrose utilization protein MalA;
GN   Name=malA; OrderedLocusNames=SPy_1298, M5005_Spy1062;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- FUNCTION: Has a role in maltotetraose utilization. {ECO:0000250}.
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DR   EMBL; AE004092; AAK34146.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ51680.1; -; Genomic_DNA.
DR   RefSeq; NP_269425.1; NC_002737.2.
DR   AlphaFoldDB; Q99ZB6; -.
DR   PaxDb; Q99ZB6; -.
DR   EnsemblBacteria; AAK34146; AAK34146; SPy_1298.
DR   KEGG; spy:SPy_1298; -.
DR   KEGG; spz:M5005_Spy1062; -.
DR   PATRIC; fig|160490.10.peg.1138; -.
DR   HOGENOM; CLU_082338_0_0_9; -.
DR   OMA; TQFRDEE; -.
DR   Proteomes; UP000000750; Chromosome.
DR   InterPro; IPR016546; Maltodextrose_util_MalA.
DR   PIRSF; PIRSF009136; Maltodextrose_util_MalA; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..271
FT                   /note="Maltodextrose utilization protein MalA"
FT                   /id="PRO_0000084558"
SQ   SEQUENCE   271 AA;  30941 MW;  7E2484B0D68539F4 CRC64;
     MPDKKQFPIS YISHCLSPRA MFASRAQFTW WQNLLIIVFL NALIMIPVTL HYANMTTYPL
     ERIVTKSLSP ITDKTYQALT QGKIEKDTFQ GQSLIRRDGE LVLAVLPTKV DLEQLASEST
     RQIIVTKKEW RFVTPDGKEL RAHVRGQQQS LADLTTVKAV KDFVNQQWYD SNKASVLGFL
     LLTFVLMVCV GTLIVIGLGA FFLTLTKRSR LFMIRNFSEG LGLMVNCLAW PSLLAIALSF
     FIQDPVLIMN CQVFGTLLML TWVFYKTQFR D