ID   MALD1_XENLA             Reviewed;         170 AA.
AC   Q6GPN9;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=MARVEL domain-containing protein 1;
GN   Name=marveld1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Nucleus {ECO:0000250}.
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DR   EMBL; BC073074; AAH73074.1; -; mRNA.
DR   RefSeq; NP_001085644.1; NM_001092175.1.
DR   AlphaFoldDB; Q6GPN9; -.
DR   DNASU; 444070; -.
DR   GeneID; 444070; -.
DR   CTD; 444070; -.
DR   Xenbase; XB-GENE-6256247; cmtm8.L.
DR   OrthoDB; 1455336at2759; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   Bgee; 444070; Expressed in lung and 12 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR013295; MAL.
DR   InterPro; IPR008253; Marvel.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR01884; MALPROTEIN.
DR   PROSITE; PS51225; MARVEL; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="MARVEL domain-containing protein 1"
FT                   /id="PRO_0000271525"
FT   TOPO_DOM        1..38
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..67
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        89..102
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..145
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        167..170
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          34..167
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
SQ   SEQUENCE   170 AA;  19221 MW;  62AB19E38DFD438C CRC64;
     MEGERPRSDT VTTTVSSHME TISLGGSIAY DRSFLRSPTG VLLLMEIMFG LLVWALIAGS
     EYFLFSAFGW VMFVAVFYWV LSVFFFLLHL TRANTRITKV PWSLVGLCFN GSAFVLYLIA
     AVVEASSVNK DVHQHHNYNS WTASSFFAFI VTVCYALSTY FSFQAWRTKS