ID   MALD_STRR6              Reviewed;         280 AA.
AC   P0A4N4; Q04699;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Maltodextrin transport system permease protein MalD;
GN   Name=malD; OrderedLocusNames=spr1920;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       maltodextrin; probably responsible for the translocation of the
CC       substrate across the membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. MalFG subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL00722.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE007317; AAL00722.1; ALT_INIT; Genomic_DNA.
DR   PIR; E98111; E98111.
DR   RefSeq; NP_359511.1; NC_003098.1.
DR   RefSeq; WP_001065636.1; NC_003098.1.
DR   AlphaFoldDB; P0A4N4; -.
DR   SMR; P0A4N4; -.
DR   STRING; 171101.spr1920; -.
DR   EnsemblBacteria; AAL00722; AAL00722; spr1920.
DR   GeneID; 60233531; -.
DR   GeneID; 66807189; -.
DR   KEGG; spr:spr1920; -.
DR   PATRIC; fig|171101.6.peg.2069; -.
DR   eggNOG; COG3833; Bacteria.
DR   HOGENOM; CLU_016047_1_2_9; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015423; F:ABC-type maltose transporter activity; IBA:GO_Central.
DR   GO; GO:0042956; P:maltodextrin transmembrane transport; IBA:GO_Central.
DR   GO; GO:0015768; P:maltose transport; IBA:GO_Central.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..280
FT                   /note="Maltodextrin transport system permease protein MalD"
FT                   /id="PRO_0000060097"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          73..265
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   280 AA;  31508 MW;  B99FE845BF728C87 CRC64;
     MNNSIKLKRR LTQSLTYLYL IGLSIVIIYP LLITIMSAFK AGNVSAFKLD TNIDLNFDNF
     KGLFTETLYG TWYLNTLIIA LITMAVQTSI IVLAGYAYSR YNFLARKQSL VFFLIIQMVP
     TMAALTAFFV MALMLNALNH NWFLIFLYVG GGIPMNAWLM KGYFDTVPMS LDESAKLDGA
     GHFRRFWQIV LPLVRPMVAV QALWAFMGPF GDYILSSFLL REKEYFTVAV GLQTFVNNAK
     NLKIAYFSAG AILIALPICI LFFFLQKNFV SGLTSGGDKG