ID   MALF1_MALFU             Reviewed;         350 AA.
AC   Q01940;
DT   04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Major allergen Mal f 1;
DE   AltName: Full=Allergen Pit o 1;
DE   AltName: Allergen=Mal f 1;
DE   Flags: Precursor;
OS   Malassezia furfur (Pityriasis versicolor infection agent) (Pityrosporum
OS   furfur).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX   NCBI_TaxID=55194;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=ATCC 42132 / M1154/77;
RX   PubMed=9210481; DOI=10.1111/j.1432-1033.1997.00181.x;
RA   Schmidt M., Zargari A., Holt P., Lindbom L., Hellman U., Whitley P.,
RA   van der Ploeg I., Haerfast B., Scheynius A.;
RT   "The complete cDNA sequence and expression of the first major allergenic
RT   protein of Malassezia furfur, Mal f 1.";
RL   Eur. J. Biochem. 246:181-185(1997).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
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DR   EMBL; X96486; CAA65341.1; -; mRNA.
DR   PDB; 2P9W; X-ray; 1.35 A; A=23-350.
DR   PDBsum; 2P9W; -.
DR   AlphaFoldDB; Q01940; -.
DR   SMR; Q01940; -.
DR   Allergome; 3364; Mala s 1.0101.
DR   Allergome; 467; Mala s 1.
DR   ABCD; Q01940; 15 sequenced antibodies.
DR   EvolutionaryTrace; Q01940; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   3D-structure; Allergen; Cell wall; Direct protein sequencing; Secreted;
KW   Signal.
FT   SIGNAL          1..22
FT   CHAIN           23..350
FT                   /note="Major allergen Mal f 1"
FT                   /id="PRO_0000021633"
SQ   SEQUENCE   350 AA;  38180 MW;  88F94FE1FF45A824 CRC64;
     MRYSTVLAAL ALLGTSAVSV LAALPDQIDV KVKNLTPEDT IYDRTRQVFY QSNLYKGRIE
     VYNPKTQSHF NVVIDGASSN GDGEQQMSGL SLLTHDNSKR LFAVMKNAKS FNFADQSSHG
     ASSFHSFNLP LSENSKPVWS VNFEKVQDEF EKKAGKRPFG VVQSAQDRDG NSYVAFALGM
     PAIARVSADG KTVSTFAWES GNGGQRPGYS GITFDPHSNK LIAFGGPRAL TAFDVSKPYA
     WPEPVKINGD FGTLSGTEKI VTVPVGNESV LVGARAPYAI SFRSWDNWKS ANIKKTKRSE
     LQNSGFTAVA DYYQGSEQGL YAVSAFFDNG AHGGRSDYPL YKLDNSILNF