ID   MALK_PHOPR              Reviewed;         369 AA.
AC   Q6LK87;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Maltose/maltodextrin import ATP-binding protein MalK {ECO:0000255|HAMAP-Rule:MF_01709};
DE            EC=7.5.2.1 {ECO:0000255|HAMAP-Rule:MF_01709};
GN   Name=malK {ECO:0000255|HAMAP-Rule:MF_01709}; OrderedLocusNames=PBPRB0420;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex MalEFGK involved in
CC       maltose/maltodextrin import. Responsible for energy coupling to the
CC       transport system. {ECO:0000255|HAMAP-Rule:MF_01709}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-maltose(out) + H2O = ADP + D-maltose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:22132, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17306, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.1;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01709};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (MalK),
CC       two transmembrane proteins (MalG and MalK) and a solute-binding protein
CC       (MalE). {ECO:0000255|HAMAP-Rule:MF_01709}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01709}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01709}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Maltooligosaccharide importer (TC 3.A.1.1.1) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01709}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG22293.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR378676; CAG22293.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041394950.1; NC_006371.1.
DR   AlphaFoldDB; Q6LK87; -.
DR   SMR; Q6LK87; -.
DR   STRING; 298386.PBPRB0420; -.
DR   EnsemblBacteria; CAG22293; CAG22293; PBPRB0420.
DR   KEGG; ppr:PBPRB0420; -.
DR   eggNOG; COG3842; Bacteria.
DR   HOGENOM; CLU_000604_1_1_6; -.
DR   OrthoDB; 1200451at2; -.
DR   Proteomes; UP000000593; Chromosome 2.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015423; F:ABC-type maltose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03301; ABC_MalK_N; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015855; ABC_transpr_MalK-like.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51245; MALK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Reference proteome; Sugar transport; Translocase;
KW   Transport.
FT   CHAIN           1..369
FT                   /note="Maltose/maltodextrin import ATP-binding protein
FT                   MalK"
FT                   /id="PRO_0000273996"
FT   DOMAIN          4..234
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01709"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01709"
SQ   SEQUENCE   369 AA;  41044 MW;  6B6EE63F093F4D51 CRC64;
     MTSVTLRNVC KAYGDNLISK NVDLEIAEGE FVVFVGPSGC GKSTLLRCIA GLEDITSGDL
     YFGKERMNDV PPSDRGVGMV FQSYALYPHL NLFDNMSFGM KLAKADKSEI KKRVNNAADI
     LQLGHLLERQ PKSLSGGQRQ RVAIGRTIVS QPNVFLLDEP LSNLDAALRV QMRIEIAKLH
     KQLGCTMIYV THDQVEAMTM AEKIVVLDGG YVSQVGKPLE LYHYPQNRFV AGFIGSPKMN
     FMSVFIEQVE DERVMVQTAD GKAFWIPVDG TTVTKGDRMS LGIRPEHLVS AEEGDTSIEG
     TVQVVEKLGY ETQVYIHLDH VDADFIYRRP DTLQVEAGDS FKVGIPAHRC HLFHSDGRAC
     RRLYQEAGI