MALM_ECOLI
ID MALM_ECOLI Reviewed; 306 AA.
AC P03841; Q2M6R7;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1988, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Maltose operon periplasmic protein;
DE Flags: Precursor;
GN Name=malM; Synonyms=molA; OrderedLocusNames=b4037, JW3997;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=2434655; DOI=10.1016/0022-2836(86)90127-0;
RA Gilson E., Rousset J.-P., Charbit A., Perrin D., Hofnung M.;
RT "malM, a new gene of the maltose regulon in Escherichia coli K12. I. malM
RT is the last gene of the malK-lamB operon and encodes a periplasmic
RT protein.";
RL J. Mol. Biol. 191:303-311(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8265357; DOI=10.1093/nar/21.23.5408;
RA Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.;
RT "Analysis of the Escherichia coli genome. IV. DNA sequence of the region
RT from 89.2 to 92.8 minutes.";
RL Nucleic Acids Res. 21:5408-5417(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-131.
RC STRAIN=K12;
RX PubMed=6086106; DOI=10.1016/0092-8674(81)90392-5;
RA Clement J.M., Hofnung M.;
RT "Gene sequence of the lambda receptor, an outer membrane protein of E. coli
RT K12.";
RL Cell 27:507-514(1981).
CC -!- FUNCTION: Not yet known. Might function in the uptake of a still
CC unidentified substrate.
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- SIMILARITY: To S.typhimurium MalM. {ECO:0000305}.
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DR EMBL; J01648; AAB59059.1; -; Genomic_DNA.
DR EMBL; X04477; CAA28166.1; -; Genomic_DNA.
DR EMBL; U00006; AAC43131.1; -; Genomic_DNA.
DR EMBL; U00096; AAC77007.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE78039.1; -; Genomic_DNA.
DR EMBL; V00298; CAA23576.1; -; Genomic_DNA.
DR EMBL; M26131; AAA24061.1; -; Genomic_DNA.
DR PIR; A25787; BVECMM.
DR RefSeq; NP_418461.1; NC_000913.3.
DR RefSeq; WP_001326641.1; NZ_SSZK01000016.1.
DR AlphaFoldDB; P03841; -.
DR SMR; P03841; -.
DR BioGRID; 4262664; 13.
DR DIP; DIP-10145N; -.
DR STRING; 511145.b4037; -.
DR jPOST; P03841; -.
DR PaxDb; P03841; -.
DR PRIDE; P03841; -.
DR EnsemblBacteria; AAC77007; AAC77007; b4037.
DR EnsemblBacteria; BAE78039; BAE78039; BAE78039.
DR GeneID; 948547; -.
DR KEGG; ecj:JW3997; -.
DR KEGG; eco:b4037; -.
DR PATRIC; fig|511145.12.peg.4152; -.
DR EchoBASE; EB0554; -.
DR eggNOG; ENOG502Z7PA; Bacteria.
DR HOGENOM; CLU_078779_1_0_6; -.
DR OMA; PDPIAKH; -.
DR PhylomeDB; P03841; -.
DR BioCyc; EcoCyc:EG10559-MON; -.
DR PRO; PR:P03841; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR010794; MalM.
DR Pfam; PF07148; MalM; 1.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal; Sugar transport; Transport.
FT SIGNAL 1..22
FT /note="Or 26"
FT /evidence="ECO:0000255"
FT CHAIN 23..306
FT /note="Maltose operon periplasmic protein"
FT /id="PRO_0000021634"
SQ SEQUENCE 306 AA; 31943 MW; BF6886F7637D2440 CRC64;
MKMNKSLIVL CLSAGLLASA PGISLADVNY VPQNTSDAPA IPSAALQQLT WTPVDQSKTQ
TTQLATGGQQ LNVPGISGPV AAYSVPANIG ELTLTLTSEV NKQTSVFAPN VLILDQNMTP
SAFFPSSYFT YQEPGVMSAD RLEGVMRLTP ALGQQKLYVL VFTTEKDLQQ TTQLLDPAKA
YAKGVGNSIP DIPDPVARHT TDGLLKLKVK TNSSSSVLVG PLFGSSAPAP VTVGNTAAPA
VAAPAPAPVK KSEPMLNDTE SYFNTAIKNA VAKGDVDKAL KLLDEAERLG STSARSTFIS
SVKGKG