ID   MALQ_CHLPN              Reviewed;         526 AA.
AC   Q9Z8L2; Q9JQ41;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=4-alpha-glucanotransferase;
DE            EC=2.4.1.25;
DE   AltName: Full=Amylomaltase;
DE   AltName: Full=Disproportionating enzyme;
DE            Short=D-enzyme;
GN   Name=malQ; OrderedLocusNames=CPn_0326, CP_0431, CpB0336;
OS   Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=83558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CWL029;
RX   PubMed=10192388; DOI=10.1038/7716;
RA   Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA   Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT   "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL   Nat. Genet. 21:385-389(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR39;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J138;
RX   PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA   Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA   Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT   "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT   Japan and CWL029 from USA.";
RL   Nucleic Acids Res. 28:2311-2314(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TW-183;
RA   Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA   Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT   "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT   other Chlamydia strains based on whole genome sequence analysis.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC         position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC         glucan.; EC=2.4.1.25;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC       {ECO:0000305}.
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DR   EMBL; AE001363; AAD18475.1; -; Genomic_DNA.
DR   EMBL; AE002161; AAF38273.1; -; Genomic_DNA.
DR   EMBL; BA000008; BAA98536.1; -; Genomic_DNA.
DR   EMBL; AE009440; AAP98269.1; -; Genomic_DNA.
DR   PIR; F86531; F86531.
DR   PIR; G72091; G72091.
DR   RefSeq; NP_224531.1; NC_000922.1.
DR   RefSeq; WP_010882974.1; NZ_LN847257.1.
DR   AlphaFoldDB; Q9Z8L2; -.
DR   SMR; Q9Z8L2; -.
DR   STRING; 115711.CP_0431; -.
DR   CAZy; GH77; Glycoside Hydrolase Family 77.
DR   EnsemblBacteria; AAD18475; AAD18475; CPn_0326.
DR   EnsemblBacteria; AAF38273; AAF38273; CP_0431.
DR   GeneID; 45050375; -.
DR   KEGG; cpa:CP_0431; -.
DR   KEGG; cpj:malQ; -.
DR   KEGG; cpn:CPn_0326; -.
DR   KEGG; cpt:CpB0336; -.
DR   PATRIC; fig|115713.3.peg.360; -.
DR   eggNOG; COG1640; Bacteria.
DR   HOGENOM; CLU_014132_2_1_0; -.
DR   OrthoDB; 814704at2; -.
DR   Proteomes; UP000000583; Chromosome.
DR   Proteomes; UP000000801; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR003385; Glyco_hydro_77.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF02446; Glyco_hydro_77; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   TIGRFAMs; TIGR00217; malQ; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Cytoplasm; Glycosyltransferase; Transferase.
FT   CHAIN           1..526
FT                   /note="4-alpha-glucanotransferase"
FT                   /id="PRO_0000170121"
SQ   SEQUENCE   526 AA;  60993 MW;  C192994118996CB3 CRC64;
     MNVLKYTKHS PSAHAWKLIG TSPKHGIYLP LFSIHTKNSC GIGEFLDLIP LISWCQKQGF
     SVIQLLPLND TGEDTSPYNS ISSVALNPLF LSLSSLPNID TIPEVAKKLQ DMHELCSTPS
     VSYTQVKEKK WAFLREYYQK CCKSSLEGNS NFSEFLESER YWLYPYGTFR AIKHHMHGEP
     INNWPKSLTD QENFPDLTKK FHDEVLFFSY LQFLCYQQLC EVKAYADQHH VLLKGDLPIL
     ISKDSCDVWY FRDYFSSSRS VGAPPDLYNS EGQNWHLPIY NFSQLAKDDY IWWKERLRYA
     QNFYSVYRLD HIIGFFRLWI WDSSGRGRFI PDNPKDYIKQ GTEILSTMLG ASSMLPIGED
     LGIIPQDVKT TLTHLGICGT RIPRWERNWE SDSAFIPLKD YNPLSVTTLS THDSDTFAQW
     WLNSPKEAKQ FAKFLHLPFQ KTLTTETQID ILKLSHESAS IFHINLFNDY LALCPDLVSK
     NLQRERINTP GTISKKNWSY RVRPSLEELA IHKKFNGYIE KILTGL