ID   MAMA_MAGMG              Reviewed;         217 AA.
AC   P0DO20; Q50224;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 8.
DE   RecName: Full=Magnetosome protein MamA {ECO:0000305};
GN   Name=mamA; Synonyms=mam22 {ECO:0000303|PubMed:8675040};
OS   Magnetospirillum magnetotacticum (Aquaspirillum magnetotacticum).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Magnetospirillum.
OX   NCBI_TaxID=188;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 31632 / DSM 3856 / NBRC 15272 / MS-1;
RX   PubMed=8675040; DOI=10.1016/0378-1119(95)00008-9;
RA   Okuda Y., Denda K., Fukumori Y.;
RT   "Cloning and sequencing of a gene encoding a new member of the
RT   tetratricopeptide protein family from magnetosomes of Magnetospirillum
RT   magnetotacticum.";
RL   Gene 171:99-102(1996).
RN   [2]
RP   SUBCELLULAR LOCATION.
RC   STRAIN=ATCC 31632 / DSM 3856 / NBRC 15272 / MS-1;
RX   PubMed=16707673; DOI=10.1128/jb.00020-06;
RA   Taoka A., Asada R., Sasaki H., Anzawa K., Wu L.F., Fukumori Y.;
RT   "Spatial localizations of Mam22 and Mam12 in the magnetosomes of
RT   Magnetospirillum magnetotacticum.";
RL   J. Bacteriol. 188:3805-3812(2006).
CC   -!- FUNCTION: Probably forms a large homooligomer on which other
CC       magnetosome subunits assemble. Required for formation of functional
CC       magnetosomes from pre-existing vesicles.
CC       {ECO:0000250|UniProtKB:Q2W8Q0}.
CC   -!- SUBUNIT: Forms round, 20 nm diameter complexes with a central cavity.
CC       Interacts with full-length Mms6 (By similarity). Probably binds MamC
CC       (By similarity). {ECO:0000250|UniProtKB:Q2W8Q0,
CC       ECO:0000250|UniProtKB:Q93DY9}.
CC   -!- INTERACTION:
CC       P0DO20; P0DO20: mamA; NbExp=6; IntAct=EBI-15851915, EBI-15851915;
CC   -!- SUBCELLULAR LOCATION: Magnetosome membrane
CC       {ECO:0000269|PubMed:16707673}; Peripheral membrane protein
CC       {ECO:0000269|PubMed:16707673}. Note=Reversibly binds to magnetosomes
CC       (PubMed:16707673). Forms oligomers that cover the surface of the
CC       magnetosome (By similarity). {ECO:0000250|UniProtKB:Q2W8Q0,
CC       ECO:0000269|PubMed:16707673}.
CC   -!- MISCELLANEOUS: This bacteria makes magnetosomes of about 43 nm diameter
CC       containing magnetite (Fe(3)O(4)). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the magnetosome MamA family. {ECO:0000305}.
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DR   EMBL; D82942; BAA11643.2; -; Genomic_DNA.
DR   AlphaFoldDB; P0DO20; -.
DR   SMR; P0DO20; -.
DR   DIP; DIP-59326N; -.
DR   GO; GO:0110143; C:magnetosome; IDA:UniProtKB.
DR   GO; GO:0110146; C:magnetosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF07719; TPR_2; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 5.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   1: Evidence at protein level;
KW   Biomineralization; Magnetosome; Membrane; Repeat; TPR repeat.
FT   CHAIN           1..217
FT                   /note="Magnetosome protein MamA"
FT                   /id="PRO_0000447734"
FT   REPEAT          12..44
FT                   /note="TPR 1"
FT                   /evidence="ECO:0000250|UniProtKB:Q2W8Q0"
FT   REPEAT          46..79
FT                   /note="TPR 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT   REPEAT          80..113
FT                   /note="TPR 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT   REPEAT          114..147
FT                   /note="TPR 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT   REPEAT          148..181
FT                   /note="TPR 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT   REPEAT          182..215
FT                   /note="TPR 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   217 AA;  23976 MW;  C90477FE83E6B483 CRC64;
     MSSKPSDILD EVTLYAHYGL SVAKKLGMNM VDAFRAAFSV NDDIRQVYYR DKGISHAKAG
     RYSQAVMLLE QVYDADAFDV DVALHLGIAY VKTGAVDRGT ELLERSLADA PDNVKVATVL
     GLTYVQVQKY DLAVPLLIKV AEANPINFNV RFRLGVALDN LGRFDEAIDS FKIALGLRPN
     EGKVHRAIAF SYEQMGRHEE ALPHFKKANE LDEGASV