ID   MAMR_MAGSA              Reviewed;          84 AA.
AC   Q2W8L5;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Magnetosome protein MamR {ECO:0000305};
GN   Name=mamR {ECO:0000303|PubMed:20212111};
GN   OrderedLocusNames=amb0973, amb1006;
OS   Magnetospirillum magneticum (strain AMB-1 / ATCC 700264).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Magnetospirillum.
OX   NCBI_TaxID=342108;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMB-1 / ATCC 700264;
RX   PubMed=16303747; DOI=10.1093/dnares/dsi002;
RA   Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.;
RT   "Complete genome sequence of the facultative anaerobic magnetotactic
RT   bacterium Magnetospirillum sp. strain AMB-1.";
RL   DNA Res. 12:157-166(2005).
RN   [2]
RP   FUNCTION, PROBABLE OPERON, AND DISRUPTION PHENOTYPE.
RC   STRAIN=AMB-1 / ATCC 700264;
RX   PubMed=20212111; DOI=10.1073/pnas.0914439107;
RA   Murat D., Quinlan A., Vali H., Komeili A.;
RT   "Comprehensive genetic dissection of the magnetosome gene island reveals
RT   the step-wise assembly of a prokaryotic organelle.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:5593-5598(2010).
RN   [3]
RP   MINIMAL MAGNETOSOME ISLAND.
RC   STRAIN=AMB-1 / ATCC 700264;
RX   PubMed=22716969; DOI=10.1111/j.1365-2958.2012.08132.x;
RA   Murat D., Falahati V., Bertinetti L., Csencsits R., Koernig A., Downing K.,
RA   Faivre D., Komeili A.;
RT   "The magnetosome membrane protein, MmsF, is a major regulator of magnetite
RT   biomineralization in Magnetospirillum magneticum AMB-1.";
RL   Mol. Microbiol. 85:684-699(2012).
CC   -!- FUNCTION: May play a role in controlling magnetite number and size but
CC       not in control of magnetite morphology. {ECO:0000305|PubMed:20212111}.
CC   -!- SUBCELLULAR LOCATION: Magnetosome {ECO:0000250|UniProtKB:Q6NE51}.
CC   -!- INDUCTION: Locus amb0973 is part of the probable 18 gene mamAB operon.
CC       {ECO:0000305|PubMed:20212111}.
CC   -!- DISRUPTION PHENOTYPE: When both copies of this protein are deleted
CC       cells have a weak magnetic response and make magnetosome membranes; the
CC       magnetosomes are less numerous and smaller. Deletion of just amb0973
CC       leads to an intermediate magnetic response and still makes magnetosome
CC       membranes (PubMed:20212111). Deletion of genes mamH to mamV (amb0961 to
CC       amb0978) gives cells with no magnetosomes and no magnetic response
CC       (PubMed:20212111). {ECO:0000269|PubMed:20212111}.
CC   -!- MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral
CC       magnetosomes of about 45 nm in diameter which contain membrane-bound
CC       crystals of magnetite (Fe(3)O(4)). {ECO:0000305}.
CC   -!- MISCELLANEOUS: Expression of just the minimal mamAB gene cluster
CC       (amb0961 to amb0978), including this gene, is sufficient to form a
CC       minimal magnetosome chain with small magnetite particles.
CC       {ECO:0000269|PubMed:22716969}.
CC   -!- SIMILARITY: Belongs to the magnetosome MamR family. {ECO:0000305}.
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DR   EMBL; AP007255; BAE49777.1; -; Genomic_DNA.
DR   EMBL; AP007255; BAE49810.1; -; Genomic_DNA.
DR   RefSeq; WP_008622632.1; NC_007626.1.
DR   AlphaFoldDB; Q2W8L5; -.
DR   EnsemblBacteria; BAE49777; BAE49777; amb0973.
DR   EnsemblBacteria; BAE49810; BAE49810; amb1006.
DR   KEGG; mag:amb0973; -.
DR   KEGG; mag:amb1006; -.
DR   HOGENOM; CLU_2523586_0_0_5; -.
DR   OMA; WDMASRD; -.
DR   OrthoDB; 1858791at2; -.
DR   Proteomes; UP000007058; Chromosome.
DR   GO; GO:0110143; C:magnetosome; ISS:UniProtKB.
DR   InterPro; IPR041657; HTH_17.
DR   Pfam; PF12728; HTH_17; 1.
PE   3: Inferred from homology;
KW   Biomineralization; Magnetosome; Reference proteome.
FT   CHAIN           1..84
FT                   /note="Magnetosome protein MamR"
FT                   /id="PRO_0000447809"
SQ   SEQUENCE   84 AA;  9283 MW;  A7EF9FA822A90F2C CRC64;
     MIWTAVIKGS ALVTFVQGAM VLVDKIFGEE ILPHRIYSSA EASQLLGMDR LEVLGLIRSG
     TIKAKKVGDN YRILGSNLVD YMNR