ID   MAN7_ORYSJ              Reviewed;         379 AA.
AC   Q2RBB1;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 3.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Mannan endo-1,4-beta-mannosidase 7;
DE            EC=3.2.1.78;
DE   AltName: Full=Beta-mannanase 7;
DE   AltName: Full=Endo-beta-1,4-mannanase 7;
DE   AltName: Full=OsMAN7;
GN   Name=MAN7; OrderedLocusNames=Os11g0118200, LOC_Os11g02600;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=16897088; DOI=10.1007/s10142-006-0034-3;
RA   Yuan J.S., Yang X., Lai J., Lin H., Cheng Z.-M., Nonogaki H., Chen F.;
RT   "The endo-beta-mannanase gene families in Arabidopsis, rice, and poplar.";
RL   Funct. Integr. Genomics 7:1-16(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->4)-beta-D-mannosidic linkages in
CC         mannans, galactomannans and glucomannans.; EC=3.2.1.78;
CC   -!- TISSUE SPECIFICITY: Expression not detected.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA91172.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF27440.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DP000010; ABA91172.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008217; BAF27440.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015616432.1; XM_015760946.1.
DR   AlphaFoldDB; Q2RBB1; -.
DR   SMR; Q2RBB1; -.
DR   STRING; 39947.Q2RBB1; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   PRIDE; Q2RBB1; -.
DR   KEGG; osa:4349615; -.
DR   InParanoid; Q2RBB1; -.
DR   OrthoDB; 1003648at2759; -.
DR   Proteomes; UP000000763; Chromosome 11.
DR   Proteomes; UP000059680; Chromosome 11.
DR   Genevisible; Q2RBB1; OS.
DR   GO; GO:0016985; F:mannan endo-1,4-beta-mannosidase activity; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR018087; Glyco_hydro_5_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR045053; MAN-like.
DR   PANTHER; PTHR31451; PTHR31451; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   2: Evidence at transcript level;
KW   Glycosidase; Hydrolase; Reference proteome.
FT   CHAIN           1..379
FT                   /note="Mannan endo-1,4-beta-mannosidase 7"
FT                   /id="PRO_0000277488"
FT   ACT_SITE        180
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250|UniProtKB:Q99036"
FT   ACT_SITE        300
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250|UniProtKB:Q99036"
FT   BINDING         64
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250|UniProtKB:B4XC07"
FT   BINDING         179
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250|UniProtKB:B4XC07"
FT   BINDING         260
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250|UniProtKB:B4XC07"
FT   BINDING         342
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250|UniProtKB:B4XC07"
SQ   SEQUENCE   379 AA;  42985 MW;  690FEA8D0B35BED0 CRC64;
     MEDAHHHHWT MVERRGTQLW ASGRPFIIHG FNTYWLMSFA ADQATRLRVT AAIAEAGLNV
     CCTWAFSDGG YRALQTAPFH YDEDVFRALD FVVSEARRHN MRLILSLCNN WEDYGGKAQY
     VRWGKEAGLD LTSEDDFFSD PTIKSYYKAF VEAVVTRINT VTNETYKDDP TILAWELINE
     PRCPSDPSGD TLQAWMEEMA SYVKSIDPVH LLEIGIEGFY GPSIPELLPV NPDEYSGHAG
     IDFIRNHQAP GIDLASIHVY SDIWLPQSIK ENHLQFVDKW MQQHIDDAAN LLGMPIVVGE
     FGVSVKDGKF GNEFREDFMK TIYRIFLSSW KEGVIGGGCL LWQLFPEGAE HMDDGYAVIF
     AKSPSTLSLL ANHLRCLEC