ID   MANS1_MACFA             Reviewed;         431 AA.
AC   Q95KG7;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=MANSC domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=MANSC1; ORFNames=QtrA-13483;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Temporal cortex;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirai M., Terao K.,
RA   Suzuki Y., Sugano S., Hashimoto K.;
RT   "Isolation of full-length cDNA clones from macaque brain cDNA libraries.";
RL   Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
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DR   EMBL; AB060888; BAB46892.1; -; mRNA.
DR   RefSeq; NP_001270652.1; NM_001283723.1.
DR   AlphaFoldDB; Q95KG7; -.
DR   SMR; Q95KG7; -.
DR   STRING; 9541.XP_005570230.1; -.
DR   GeneID; 102146646; -.
DR   CTD; 54682; -.
DR   eggNOG; ENOG502RZBP; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR013980; MANSC_dom.
DR   InterPro; IPR011106; MANSC_N.
DR   Pfam; PF07502; MANEC; 1.
DR   SMART; SM00765; MANEC; 1.
DR   PROSITE; PS50986; MANSC; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..431
FT                   /note="MANSC domain-containing protein 1"
FT                   /id="PRO_0000021637"
FT   TOPO_DOM        27..385
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        409..431
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          33..117
FT                   /note="MANSC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00341"
FT   REGION          236..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        31
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        222
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        251
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        327
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        352
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   431 AA;  47105 MW;  BF10996E87F76C69 CRC64;
     MFFGGKGSLT YTLVIICFLT LRLAASQNCL NKSLEDVVID IQSSLSKGIR GNEPIYTSTQ
     EDCINSCCST KIISGDKACN FMIFDTRKIA RRPNCYLFFC PNEEACPLKP AKGLRSYRII
     RDFPSLTRNL PSQELPQEDS LLPGQFSQAV TPLARHHIVY SKPTDISWRE TLPQKFGSSD
     HLEKLFNMDK ASAQLLVYKE KGHSQSSQIS SDQEIAHLLP ENVSVFPATV AVASPHTTSA
     TPKPAIRLPT NASVTPSGTS QPQLATTSPP VTTVTSQPPT TLISTGFTRA VATLQAMATT
     AVLTTTFQAP TDLKGSLETI PFTEISNLTL NTGNVYNPTA LSMSNVKSSA TNKTASWEGR
     EASPGRSSQG NVPENQYGLP FEKWLLIGSL LFGVLFLVIG LVLLGRILSE SLRRKRYSRL
     DYLINGIYVD I