MAPE_PINMG
ID MAPE_PINMG Reviewed; 140 AA.
AC Q14WA6;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 3.
DT 25-MAY-2022, entry version 23.
DE RecName: Full=Perlin matrix protein;
DE Flags: Precursor;
OS Margaritifera margaritifera (Freshwater pearl mussel).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pterioida; Pterioidea; Pteriidae; Pinctada.
OX NCBI_TaxID=102329;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Montagnani C., Fleury E., Belliard C., Piquemal D., Flaven E.,
RA Cochennec-Laureau N.;
RT "Characterization of perline and calcine, two conserved shell matrix genes
RT implicated in biomineralization processes in the pearl oyster Pinctada
RT margaritifera.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be specifically involved in the formation of the nacreous
CC layer. {ECO:0000250}.
CC -!- SUBUNIT: Heterooligomer; disulfide-linked. Pif97, Pif80, N16 and other
CC proteins form a complex (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Component of conchiolin, the organic matrix of
CC nacre. Only expressed in the dorsal region of the mantle.
CC -!- SIMILARITY: Belongs to the N16 matrix protein family. {ECO:0000305}.
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DR EMBL; DQ665305; ABG24165.3; -; mRNA.
DR AlphaFoldDB; Q14WA6; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Disulfide bond; Extracellular matrix; Secreted; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000250"
FT CHAIN 27..140
FT /note="Perlin matrix protein"
FT /id="PRO_0000379786"
SQ SEQUENCE 140 AA; 16314 MW; 2E82C932B5C72C2D CRC64;
MTCTLRLTVA ALVLLGICHL SRPVAAYQKC ARYWYCWLPY DIERDRYDDG YRLCCYCRNA
WTPWQCREDE QFERLRCGSR YYTLCCYTED DNGNGNGNGN GYGNGNGNGN GNNYLKYLFG
GNGNGNGEFW EEYIDERYDK